Sanofi

This study tested a combination of two drugs, isatuximab and cemiplimab, in people with certain types of lymphoma that had come back or not responded to treatment. The goal was to find a safe dose and see if the combination could shrink tumors. The trial was stopped early, so res…

This study tested a new hormone therapy, amcenestrant, at two different doses against the standard drug letrozole in postmenopausal women with a common type of early breast cancer (ER+/HER2-). The goal was to see if amcenestrant could better slow tumor growth before surgery. The …

This study tested a drug called tusamitamab ravtansine in 50 adults with advanced breast or pancreatic cancer that had spread. The goal was to see if the drug could shrink tumors or slow the disease. The trial was stopped early, and results are limited.

This study tested a new drug called SAR444245 combined with other cancer treatments for people with head and neck cancer that had spread or come back. The goal was to see if the combination could shrink tumors. The study was stopped early and included 59 adults.

This study tested an experimental drug called SAR443216 in 44 adults with advanced HER2-positive solid tumors (like breast, lung, or stomach cancer) that had stopped responding to other treatments. The goal was to find a safe dose and see if it could shrink tumors. However, the t…

This study tested a new drug called SAR444245 combined with other cancer treatments in 106 adults with advanced non-small cell lung cancer or pleural mesothelioma. The goal was to see if the combination shrank tumors. The trial was terminated early, so results are limited.

This study tested a new drug (tusamitamab ravtansine) combined with pembrolizumab and chemotherapy for people with a specific type of advanced lung cancer (non-squamous NSCLC) that has a marker called CEACAM5. The goal was to see if the combination was safe and could shrink tumor…

This study looked at whether the antibiotic teicoplanin could treat diarrhea and colitis caused by C. difficile bacteria. It involved 50 adults with mild to severe infection. The goal was to stop diarrhea and prevent it from coming back, but the study was ended early.

This study tested a new drug called SAR444200, alone or with other medicines, in adults with advanced solid tumors that had spread and were no longer responding to standard treatments. The trial was stopped early, but researchers were checking safety and whether the drug could sh…

This study tested a drug called amlitelimab in 90 adults with moderate to severe hidradenitis suppurativa (HS), a painful skin condition that causes boils and tunnels under the skin. The goal was to see if the drug could reduce the number of abscesses and inflamed bumps by at lea…

This study tested a drug called tolebrutinib for people with moderate-to-severe generalized myasthenia gravis, a condition that causes muscle weakness. The trial aimed to see if the drug could improve daily living activities compared to a placebo. However, the study was terminate…

This early-phase study tested the safety of an experimental drug called DNL747 in 15 people with ALS. The trial was stopped early, so we don't know if the drug helps control the disease or ease symptoms. The main goal was to check for side effects, not to measure any treatment be…

This study tested a new drug (SAR444245) combined with an immunotherapy (cemiplimab) in 46 people with advanced melanoma or skin squamous cell carcinoma that could not be removed by surgery. The goal was to see if the combination shrank tumors. The trial was terminated early, so …

This early-phase trial tested an experimental drug, SAR441000, injected directly into tumors, either alone or with another drug (cemiplimab), in 77 adults with advanced solid tumors that had no standard treatment options. The goal was to find a safe dose and see if it could shrin…

This study tested an experimental drug called SAR444245, alone or with pembrolizumab, in 14 people aged 12 and older with B cell lymphoma that returned or didn't respond to prior treatments. The goal was to see if the drug could shrink tumors. The trial was terminated early, so r…

This study tested a drug called isatuximab in 23 people waiting for a kidney transplant. The goal was to see if it could safely lower certain immune system antibodies that make it harder to find a matching donor. The study was stopped early, so the full results are not available.

This study tested a new drug, tusamitamab ravtansine, against standard chemotherapy (docetaxel) in 389 adults with advanced non-small-cell lung cancer that had stopped responding to previous treatments. The drug targets a specific marker (CEACAM5) on cancer cells. The trial was t…

This study aimed to see if a medicine called efanesoctocog alfa (Altuviiio) helps people with moderate or severe hemophilia A achieve their personal goals and be more physically active. It planned to enroll 35 people aged 12 to 50 who were starting this preventive treatment. Howe…

This early-stage study tested a single dose of an experimental drug called SAR439459 in 16 adults with osteogenesis imperfecta (brittle bone disease). The goal was to check safety and see if the drug could improve bone density. The study was terminated early, so results are limit…

This early-stage study tested an experimental oral drug called amcenestrant, alone or with other cancer drugs, in 136 postmenopausal women with advanced estrogen receptor-positive (ER+) breast cancer that had spread. The goal was to find safe doses and see if the drug could shrin…

This study compared two long-acting insulins (Gla-300 and IDeg-100) in adults with type 2 diabetes and kidney disease who had never used insulin before. The goal was to see which one controls blood sugar better with fewer risks. The trial was stopped early, so results are limited…

This study looked at whether starting venglustat early could slow kidney growth in people with a fast-progressing form of polycystic kidney disease (ADPKD). It enrolled 24 adults who had already completed a previous venglustat study. The trial was stopped early because the drug d…

This study tested an oral drug called SAR443820 in 174 adults aged 18 to 60 with multiple sclerosis (MS). The goal was to see if the drug could lower a marker of nerve damage in the blood. The study was stopped early because the drug did not work better than a placebo. No major s…

This study tested a new drug called amcenestrant against standard hormone therapies for people with a common type of advanced breast cancer (ER+/HER2-). The goal was to see if amcenestrant could slow cancer growth better than usual treatments. The trial included 367 adults whose …

This early-stage study tested a new drug called SAR443579 in adults and children with blood cancers like acute myeloid leukemia and others that had come back or not responded to treatment. The goal was to find a safe dose and see if the drug could shrink the cancer. The study was…

This early-phase study tested a new type of immune cell therapy, called SAR445419, in adults with acute myeloid leukemia that returned or didn't respond to treatment. Participants received chemotherapy followed by infusions of donor natural killer (NK) cells over two weeks. The m…

This study tested a new drug, amcenestrant, combined with palbociclib against the standard letrozole plus palbociclib for people with a common type of advanced breast cancer (ER+/HER2-). The goal was to see if the new combo could delay cancer growth longer. The trial was stopped …

This study tested a drug called isatuximab added to standard chemotherapy for children aged 28 days to under 18 years whose leukemia (ALL or AML) had returned or stopped responding to treatment. The goal was to see if the combination could help achieve complete remission. The tri…

This study aimed to see if hydroxychloroquine could reduce the amount of virus in the nose and throat of adults with mild COVID-19. Only 8 people took part before the study was stopped early. The trial compared the drug to a placebo (a dummy pill) and looked at safety and symptom…

This study tested a new drug, amcenestrant, against an older drug, tamoxifen, in people with hormone receptor-positive early breast cancer who had to stop their initial hormone therapy due to side effects. The goal was to see if amcenestrant could better prevent the cancer from c…

This study tested a new drug called SAR444656 in 70 adults with moderate to severe hidradenitis suppurativa (HS), a painful skin condition. The goal was to see if the drug could reduce abscesses and inflamed bumps better than a placebo over 16 weeks. However, the trial was termin…

This study tested an experimental drug called SAR444656 in 70 adults with moderate to severe eczema that wasn't controlled by creams or ointments. Participants received one of three doses of the drug or a placebo for 16 weeks. The goal was to see if the drug could reduce skin red…

This study looked at how the drug amcenestrant moves through the body in women aged 40-75 with mild or moderate liver problems, compared to women with healthy livers. The goal was to understand dosing and safety. Only 13 women took part before the study was stopped early.