New drug shows promise in shrinking breast cancer tumors before surgery
NCT ID NCT04191382
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 25 times
Summary
This study tested a new hormone therapy, amcenestrant, at two different doses against the standard drug letrozole in postmenopausal women with a common type of early breast cancer (ER+/HER2-). The goal was to see if amcenestrant could better slow tumor growth before surgery. The study was stopped early, and results are not yet conclusive.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Investigational Site Number 0560001
Leuven, 3000, Belgium
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Investigational Site Number 0560002
Namur, 5000, Belgium
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Investigational Site Number 2500001
Nantes, 44093, France
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Investigational Site Number 2500002
Saint-Cloud, 92210, France
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Investigational Site Number 2500003
Toulouse, 31059, France
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Investigational Site Number 2500004
Paris, 75010, France
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Investigational Site Number 3800001
Milan, 20141, Italy
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Investigational Site Number 3800002
Milan, 20132, Italy
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Investigational Site Number 3800004
Meldola, 47014, Italy
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Investigational Site Number 3920001
Yokohama, Japan
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Investigational Site Number 3920002
Osaka, Japan
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Investigational Site Number 3920003
Sapporo, Japan
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Investigational Site Number 6430002
Saint Petersburg, 197758, Russia
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Investigational Site Number 6430003
Saint Petersburg, 194156, Russia
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Investigational Site Number 6430004
Moscow, 119991, Russia
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Investigational Site Number 6430006
Moscow, 117186, Russia
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Investigational Site Number 6430007
Saint Petersburg, 195271, Russia
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Investigational Site Number 7240001
Madrid, 28041, Spain
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Investigational Site Number 7240002
Valencia, 46010, Spain
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Investigational Site Number 7240003
Córdoba, 14004, Spain
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Investigational Site Number 7240005
Barcelona, 08003, Spain
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Investigational Site Number 8040001
Uzhhorod, 88000, Ukraine
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Investigational Site Number 8040002
Vinnytsia, 21029, Ukraine
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Investigational Site Number 8040004
Kharkiv, 61166, Ukraine
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Investigational Site Number 8040005
Zaporizhzhya, 69040, Ukraine
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Investigational Site Number 8400005
Lincoln, Nebraska, 68506, United States
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Investigational Site Number 8400007
Hato Rey, 00917, Puerto Rico
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Investigational Site Number 8400010
Los Angeles, California, 90095, United States
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Investigational Site Number 8400012
Tacoma, Washington, 98405, United States
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Investigational Site Number 8400014
Tucson, Arizona, 85724, United States
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Investigational Site Number 8400016
Winston-Salem, North Carolina, 27157, United States
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Investigational Site Number 8400018
Fort Wayne, Indiana, 46804, United States
Conditions
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