Royal Marsden Nhs Foundation Trust

This early-phase study tested whether combining the immunotherapy drug pembrolizumab with the chemotherapy gemcitabine is safe for people with two rare types of soft tissue sarcoma (leiomyosarcoma and undifferentiated pleomorphic sarcoma). 25 participants with advanced or inopera…

This early-phase study tested whether combining the immunotherapy drug pembrolizumab with standard palliative radiotherapy is safe for people with advanced lung cancer. 24 participants received both treatments, then continued pembrolizumab alone. The goal was to find the safest d…

This study tested a combination of two drugs, crizotinib (a tablet) and fulvestrant (an injection), in 33 people with advanced lobular breast cancer that is estrogen-receptor positive. It also tested crizotinib alone in people with diffuse gastric cancer, triple-negative lobular …

This early-phase trial tested whether adding the drug avelumab (compound 451238) to radiation therapy is safe for people with advanced soft-tissue sarcoma that has spread. Twelve adults with at least two tumors not curable by standard treatments took part. The main goal was to ch…

This study tested a precise type of radiation (SBRT) in 86 men with prostate cancer that had started growing despite hormone therapy. The goal was to see if zapping just the growing spots could slow the cancer down and delay the need for chemotherapy. The researchers also looked …

This study followed 388 women with advanced ovarian, fallopian tube, or peritoneal cancer who were taking niraparib as a maintenance treatment to keep their cancer from coming back. Researchers observed how well patients tolerated the drug in everyday clinical practice, without g…

This study looked at 153 adults with cancer who were tested for COVID-19. Researchers checked their blood for antibodies at several time points to see how well the tests worked. The goal was to learn more about COVID-19 in cancer patients and improve how doctors manage their care…