Northwell Health

This study tests whether lisinopril, a common blood pressure medicine that works in the brain, can improve memory and concentration problems in people with lupus. About 36 adults with lupus will take either lisinopril or another similar drug for 12 months. Researchers will measur…

This study tests a device called PureWick to help women aged 50 and older who wake up to urinate at least twice a night. The goal is to see if using the device reduces the number of nighttime bathroom trips and the risk of falls. Participants will use the device at home and be fo…

This study tests whether injecting Botox into the bladder muscle can reduce urine leakage in women with stress urinary incontinence. About 20 women who have not improved with other treatments will receive the injection and be monitored for changes in leakage and side effects. The…

This study tests a new website tool called WeCareToFeedDysphagia to see if it reduces feelings of burden in caregivers of people with Alzheimer's or related dementias who also have trouble swallowing. About 802 caregivers will either get access to the tool or not, and all will ha…

This 12-week study tests whether personalized text messages can help 100 caregivers of people with Alzheimer's disease build a habit of walking at least 250 steps each hour. The goal is to reduce the time caregivers spend sitting and improve their health. Participants receive tex…

This study aimed to see if giving a mix of cold saline, minocycline, and magnesium directly to the brain right after a stroke clot is removed is safe and possible. It was designed for adults aged 18-90 having a major stroke. However, the trial was withdrawn before enrolling any p…

This study tests whether personalized text messages can help 100 caregivers of people with Alzheimer's disease develop a daily walking habit. Over 12 weeks, participants receive texts designed to encourage them to walk at least 1,000 steps in a set period each day. The goal is to…

This study tests whether a device called Urolift, which lifts the prostate away from the urethra, can reduce urinary problems like frequent urination and pain after radiation therapy for prostate cancer. About 20 men with both prostate cancer and an enlarged prostate (BPH) will r…

This study looks at how the immune system of people with chronic spinal cord injuries responds to flu and COVID-19 vaccines. Researchers will compare their vaccine responses to those of healthy individuals. The goal is to understand why people with spinal cord injuries are more p…

This small pilot study is testing whether a non-invasive device that stimulates the vagus nerve through the ear can change the heart's electrical signals. Ten adults already scheduled for a heart procedure will receive the stimulation while doctors measure various heart timing in…

This study follows 32 people with Parkinson's disease to see if those with a specific gene change (GBA mutation) have faster changes in brain activity over time. Participants will have brain scans and tests of movement and thinking. The goal is to understand how genes influence t…