National Institute Of Neurological Disorders And Stroke (ninds)

This early-stage study tests a drug called acamprosate in 30 adults with ALS who have a specific gene mutation (C9orf72). The main goal is to see if the drug is safe. Researchers will also check if it helps slow the disease by measuring changes in muscle function and daily living…

This study tests a brain implant called deep brain stimulation (DBS) for people with severe focal hand dystonia, including musicians. Five adults who have not improved with botox will have surgery to place electrodes in movement-related brain areas. The goal is to see if the devi…

This study tests whether a treatment called IVIG (human immunoglobulin) can help with ongoing brain and nerve symptoms after COVID-19, such as dizziness, memory problems, or weakness. About 45 adults who had COVID-19 at least 12 weeks ago will receive either IVIG or a placebo (sa…

This study looks at how the brain forms and recalls memories by recording brain activity in people with epilepsy who are already having brain surgery. Participants do memory tasks like recalling words or navigating a virtual town while their brain signals are recorded. The goal i…

This study follows 250 people with von Hippel-Lindau disease to learn how brain and spinal cord tumors grow over time. Participants aged 8 to 75 will have MRI scans and blood tests every 6 months for up to 5 years. The goal is to find out which tumors are likely to cause problems…

This study aims to improve how doctors test for autonomic failure, a condition where the body's automatic functions like blood pressure control don't work properly. About 89 adults with Parkinson's disease, multiple system atrophy, or related conditions will undergo a series of t…

This study looks at people with inherited nerve and muscle disorders that begin in childhood, along with their family members and healthy volunteers. The goal is to better understand how these diseases progress over time and to find better ways to measure changes in patients. Res…