National Cancer Centre, Singapore

This study is testing a new, non-invasive treatment called histotripsy for people with liver tumors. It uses focused sound waves to destroy tumor tissue. The main goals are to see if the treatment is safe and if it can control the tumors for at least six months. Researchers will …

This study is testing a personalized vaccine designed to prevent liver cancer from coming back after surgery. The vaccine is custom-made for each patient using their own tumor and immune cells, and is given alongside an immunotherapy drug called nivolumab. The goal is to see if t…

This study is testing whether a combination of two existing drugs, pembrolizumab and olaparib, can help control a type of blood cancer called peripheral T-cell lymphoma (PTCL) in adults for whom prior treatments have stopped working. The goal is to see if this drug pair can shrin…

This study is testing if a two-step treatment works better for controlling advanced liver cancer that is still confined to the liver. All patients first receive a targeted radiation treatment directly to the liver tumors. Then, half receive a combination of two immunotherapy drug…

This study is testing whether a 6-month exercise program can help prevent breast cancer from returning in survivors. It will involve over 2,100 women who have completed surgery and other treatments. Participants will either follow a supervised exercise plan or be observed, to see…

This study is testing a combination of three drugs—lenvatinib, pembrolizumab, and letrozole—for people with advanced breast cancer that is hormone-positive and has stopped responding to standard hormone treatments. The goal is to see if this new combination can shrink tumors and …

This study is testing whether a 12-week program of exercise therapy, with or without cognitive behavioral therapy (CBT), can help reduce fatigue in women who have been treated for breast cancer. The researchers want to see if these programs are practical and acceptable to patient…

This study is testing a smartphone app designed to help women with breast cancer cope during chemotherapy. The app provides information and support to help manage anxiety, depression, and improve quality of life. Researchers will see if the app is easy to use and helpful for 40 w…