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New study aims to help cancer patients and families avoid crises with early coaching calls

NCT ID NCT06044441

Symptom relief Sponsor: National Cancer Centre, Singapore Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a program called ENABLE-SG, which provides phone-based coaching sessions to people recently diagnosed with advanced cancer and their caregivers. The goal is to help them manage stress, symptoms, and planning early on, rather than waiting for a crisis. Researchers will measure whether this approach improves quality of life for both patients and caregivers.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ENABLE-SG model (structured psycho-educational sessions with a health coach delivered over the phone)
What this could lead to
If it works, this could provide a proven way to improve quality of life for advanced cancer patients and their caregivers by offering early, proactive support.
What could go wrong
This is a single-site study in Singapore, so results may not apply elsewhere. The program is behavioral, so benefits may be modest and depend on participant engagement.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 715 people

The number the study aims to enrol. It can still change while the study runs.

Started

Dec 2023

Expected to finish

Aug 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

21 to 120 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Inclusion criteria for patients: 1. Adult aged 21 and above 2. Within 60 days of being informed of an advanced cancer diagnosis, defined as metastatic or recurrent/ progressive Stage III/IV solid tumour 3. Able to speak English or Chinese 4. Able to provide informed consent 5. Patients will NOT need to have a caregiver willing to participate in the ENABLE-SG programme. * Inclusion criteria for caregivers: 1. Adult aged 21 and above 2. Self-endorsing or identified by the enrolled patient as an unpaid spouse/partner, relative or friend who knows them well and who provides regular support (at least 7 hours a week) due to their cancer and who does not have to live in the same dwelling 3. Caring for a patient with advanced cancer (see definition under patient inclusion criteria above) 4. Able to speak English or Chinese. 5. Able to provide informed consent * Inclusion criteria for healthcare professions: 1. 21 years or older. 2. Approached to participate in the ENABLE-SG study 3. Able to provide informed consent Exclusion Criteria: * Exclusion criteria for patients: 1. Medical record documentation of an active severe mental illness, dementia, active suicidal ideation, uncorrected hearing loss 2. Unable to complete patient-reported outcome measures 3. Has been reviewed by palliative care services in the current model of palliative care. * Exclusion criteria for caregivers: 1. Self-reported severe mental illness, dementia, active suicidal ideation, uncorrected hearing loss 2. Unable to complete caregiver-reported outcomes. * Exclusion criteria for healthcare professional: 1. Healthcare professionals that are not providing care for cancer patients. 2. Unable to complete interviews.

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Conditions

The condition(s) this trial relates to.

cancer neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Neoplasms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • National Cancer Centre Singapore

    RECRUITING

    Singapore, 168583, Singapore

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