Exercise after breast cancer: a new prescription for survival?
NCT ID NCT05957068
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests whether a 24-week exercise program combining brisk walking and strength training can improve survival in women with early-stage breast cancer. Over 2,000 participants will be enrolled within 8 weeks of finishing surgery or chemotherapy. The program starts with in-person sessions and continues with remote or gym-based training. Researchers will track cancer recurrence and overall survival.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Exercise programme (aerobic exercise and strength training)
- What this could lead to
- If successful, this could show that regular exercise after breast cancer treatment helps reduce the risk of cancer returning and improves overall survival.
- What could go wrong
- This is a behavioral intervention, not a drug, so results may vary widely. The study is large but still observational in nature regarding survival outcomes, and exercise adherence may be challenging for some participants.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 2,156 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2023
- Expected to finish
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May 2033
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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21 to 99 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients with histologically or cytologically proven stage 1, 2, or 3 breast cancer * Patients who have undergone curative breast surgery * Patients who have received (neo)adjuvant chemotherapy (if given) and/or radiotherapy (if given) * Females aged 21 years and older * ≤ 8 weeks from breast surgery, or the last adjuvant chemotherapy or radiotherapy session, whichever is latest. Exclusion Criteria: * Cardiovascular, respiratory, musculoskeletal problems that preclude moderate physical activity. * Major medical problems that are deemed by the investigator to be unsuitable for enrollment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
3 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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National Cancer Centre
RECRUITINGSingapore, 168583, Singapore
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National University Hospital
RECRUITINGSingapore, 119074, Singapore
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Singapore General Hospital
RECRUITINGSingapore, 169608, Singapore
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