Menoufia University

This trial tests whether plasma exchange (a blood-cleaning procedure) given every other day works as well as daily sessions for children with autoimmune encephalitis, a condition where the immune system attacks the brain. The study involves 22 children who are randomly assigned t…

This trial investigates whether giving a blood thinner (enoxaparin) to critically ill children with a central venous line can reduce complications like clots and blockages. About 80 children in the pediatric ICU will be randomly assigned to receive either enoxaparin or standard c…

This trial investigates whether therapeutic plasma exchange — a procedure that filters the blood to remove harmful substances — can reduce deaths in critically ill children with severe sepsis or septic shock. Participants are randomly assigned to receive either standard sepsis ca…

This study tests whether 3D-printed resin crowns and bridges work as well as traditional milled zirconia ones for people with dental implants. Sixty adults who need one or two implant-supported restorations in the lower front jaw will receive either a 3D-printed resin or a zircon…

This study looks at how well a full set of dental implants (All-on-X) works for people with bone loss in the upper jaw. Researchers will check implant survival and gum health over 2 years using special stackable guides for surgery. The goal is to see if this method helps patients…

This study tests a fully digital method for full-mouth dental rehabilitation in 10 adults aged 20-45 with bite problems, missing teeth, or smile concerns. The approach uses 3D scans of the teeth, face, and jaw to plan treatment, which may include tooth movement, guided implant pl…

This study looks at a new way to place dentures in the lower jaw using computer-guided surgery. The goal is to see if these implant-supported dentures help keep the jawbone healthy and last for at least 3 years. 40 adults aged 40-75 with no teeth in the lower jaw and enough bone …

This study tests whether a liver ultrasound measurement — the hepatic vein systolic filling fraction — can accurately assess right heart function in critically ill patients on mechanical ventilators. Researchers will compare this new method to the standard TAPSE measurement in 11…

This study tests whether a fluorescent starch nano-particle mouth rinse, combined with saliva biomarkers, can detect the earliest stages of tooth decay more accurately than a traditional visual exam. Sixty adults with at least one suspected early enamel lesion will be evaluated u…

This study compares two prostate biopsy techniques—cognitive-targeted and MRI-ultrasound fusion—to see which detects prostate cancer more accurately. About 80 men with elevated PSA and suspicious MRI findings will participate. Results may help doctors choose the best biopsy metho…

Researchers are testing whether a cervical erector spinae plane block, a type of nerve block that numbs pain without weakening the arm, reduces pain after surgery to repair a broken upper arm bone near the shoulder. The trial enrolls 44 adults scheduled for this operation under g…

Researchers are testing whether adding a lidocaine infusion to a nerve block in the chest and abdomen reduces the amount of fentanyl needed during gastric bypass surgery. The trial enrolls 100 obese adults scheduled for laparoscopic Roux-en-Y gastric bypass. Participants receive …

This trial compares two ultrasound-guided nerve blocks—the erector spinae plane block and the external oblique intercostal plane block—to see which better supports breathing recovery after liver resection surgery. Adults aged 18-75 scheduled for elective liver surgery will be ran…

This study will test whether adding two different doses of dexmedetomidine to the standard epidural drug bupivacaine can provide effective labor pain relief while using less bupivacaine. Researchers plan to enroll 140 women in early labor. The goal is to see if this approach redu…

This study compares three volumes of a nerve block (M-TAPA) to see which provides the best pain relief after laparoscopic sleeve gastrectomy. Sixty adults undergoing this weight-loss surgery will receive one of three volumes of bupivacaine. The goal is to find the optimal volume …

This study compares two ways to remove a kidney: laparoscopic (keyhole) surgery and open surgery. Researchers will look at how long patients stay in the hospital, blood loss, complications, and costs. The study includes 60 adults with a nonfunctioning kidney or early-stage kidney…

This trial tests whether a smartphone-based photogrammetry system (T-Marker) can match or beat a specialized intraoral scanner with splinting bodies (IoConnect) for recording implant positions in people with full-arch dental implants. Each participant will be scanned with both me…

This study will compare deep versus moderate muscle relaxation during open hysterectomy in 88 women. Researchers want to see if deeper relaxation reduces pain, the need for opioid painkillers, and inflammation after surgery. The goal is to find the best approach to improve recove…

This study looks at 60 people with septic shock, a severe infection that causes dangerously low blood pressure. Doctors need to give fluids carefully, but too much can be harmful. The trial compares two methods—a heart monitor (cardiometry) and an ultrasound of a large vein (IVC …