Lab test reveals best cleaners for High-Tech dentures
NCT ID NCT07672847
First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time
Summary
This laboratory study examines how three common denture disinfectants—sodium hypochlorite, chlorhexidine, and effervescent alkaline peroxide tablets—affect the surface roughness, hardness, and dimensional stability of two modern denture base materials: PMMA and PEEK. Researchers will compare these effects against a control group soaked in distilled water. The goal is to identify which cleaning method best preserves the quality and fit of CAD/CAM milled dentures.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- denture disinfectants (sodium hypochlorite, chlorhexidine, effervescent alkaline peroxide tablet)
- What this could lead to
- If certain disinfectants prove safe for these materials, it could help denture wearers choose cleaning methods that keep their dentures in good shape longer.
- What could go wrong
- This is a lab study on material samples, not on real dentures in people's mouths. Results may not reflect everyday use or long-term effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 88 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Oct 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Used prefabricated CAD-CAM blocks (PMMA and PEEK, dental grade) * All specimens milled using standardized CAD-CAM protocols * Materials from same brand, batch and shade per group * All specimens polished to a clinical high gloss standard * Used standardized specimen geometry Exclusion Criteria: * Specimens fabricated using a method other than CAD-CAM milling * Use blocks from different manufacturer, batches or shades within the same test group * Use specimens with fabrication defects (visible porosity, cracks, internal voids) or obvious milling errors (tool chattering marks, incomplete milling) * Specimens with dimensional inaccuracy * Specimens subjected to incorrect immersion time, temp or concentration of disinfectant * Use contaminated, not freshly prepared or expired disinfectant solutions
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Menoufia University
Shibīn al Kawm, Egypt
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