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Could deeper muscle relaxation during hysterectomy reduce pain and opioid use?

NCT ID NCT07485517

Knowledge-focused Sponsor: Menoufia University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Aug 14, 2026 · Updated 4 times

Summary

This study will compare deep versus moderate muscle relaxation during open hysterectomy in 88 women. Researchers want to see if deeper relaxation reduces pain, the need for opioid painkillers, and inflammation after surgery. The goal is to find the best approach to improve recovery and comfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
rocuronium bromide
What this could lead to
If it works, this could help doctors choose the best level of muscle relaxation during surgery to reduce pain and opioid use.
What could go wrong
This is a small, early-stage study with only 88 participants, so results may not apply to all patients. It measures temporary effects, not long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 88 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Women who will be admitted to undergo elective hysterectomy ,-ASA grade I or II, * Body mass index (BMI) of \<35 kg/m2 Exclusion Criteria: hemoglobin concentration of ≤7 gm%, * the presence of neuromuscular disorders * uncontrolled medical diseases * autoimmune diseases, maintenance on immunosuppressant therapy for any indication * refusal to sign the written consent

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Change in serum levels of the estimated inflammatory cytokines Pain scores Po morphine Surgeons' rating Total dose of io fentanyl

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Faculty of Medicine Menoufia University

    RECRUITING

    Menoufia, Eg.mn, 32511, Egypt

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