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Finding the right dose: nerve block study aims to cut opioid use after Weight-Loss surgery

NCT ID NCT07510347

Symptom relief Sponsor: Menoufia University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares three volumes of a nerve block (M-TAPA) to see which provides the best pain relief after laparoscopic sleeve gastrectomy. Sixty adults undergoing this weight-loss surgery will receive one of three volumes of bupivacaine. The goal is to find the optimal volume that delays the need for additional pain medication and reduces opioid use.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bupivacaine
What this could lead to
If successful, this could identify the best volume of local anesthetic for pain relief after sleeve gastrectomy, reducing opioid use and improving recovery.
What could go wrong
This is a small, early-phase trial with only 60 participants, so results may not apply to all patients. The nerve block may not provide better pain control than standard methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 60 people

The number the study aims to enrol. It can still change while the study runs.

Started

May 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria Patients will be eligible for the study if they meet the following criteria: 1. Adults aged \> 20 years to 60 years. 2. Scheduled for elective laparoscopic sleeve gastrectomy. Exclusion Criteria Patients will be excluded from the study if any of the following conditions apply: 1. American Society of Anesthesiology (ASA) ASA \> class 2. 2. History of chronic pain or opioid use for more than 3 months before surgery. 3. Previous major abdominal surgery (which may affect M-TAPA efficacy). 4. Known hypersensitivity or allergy to local anesthetics (e.g., bupivacaine). 5. Coagulopathy or ongoing anticoagulant therapy that could increase bleeding risk. 6. Local infection at the injection site. 7. Neuromuscular disorders affecting pain perception. 8. Patient with mental or psychiatric disorders.

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Conditions

The condition(s) this trial relates to.

obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

TIME

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Menofia faculty of medicine

    RECRUITING

    Shibīn al Kawm, Menofia, 32511, Egypt

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