Keyhole vs. open: which kidney surgery is better and cheaper?
NCT ID NCT07461090
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two ways to remove a kidney: laparoscopic (keyhole) surgery and open surgery. Researchers will look at how long patients stay in the hospital, blood loss, complications, and costs. The study includes 60 adults with a nonfunctioning kidney or early-stage kidney cancer who need surgery.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Feb 2026
An estimate. Start dates often move.
- Expected to finish
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Feb 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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1 year and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * American Society of Anesthesiology score 1-3. * Indication for : * Simple total nephrectomy or hemi nephrectomy: benign chronic inflammatory non-functioning kidney * Partial nephrectomy: localized renal mass ≤7 cm suitable for nephron-sparing surgery. * Radical nephrectomy or Radical nephrouretrectomy with bladder cuff: localized renal tumor requiring complete nephrectomy without major vascular invasion. * Patient deemed fit for general anesthesia and surgery. * Patient provides written informed consent. Exclusion Criteria: * emergency surgery, dialysis-dependent patients, planned hybrid procedures. * Patients with incomplete data * Patients with metastatic disease at presentation. * Prior extensive ipsilateral retroperitoneal surgery or severe adhesions precluding Laparoscopy. * Need for concomitant major procedures (eg, large bowel resection) at index operation. * Locally advanced tumor with obvious major vascular involvement requiring complex vascular reconstruction. * Uncorrected coagulopathy. * Pregnancy or Obese patient (BMI \> 40) * Inability to provide informed consent or comply with follow-up.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Menoufia Faculty of Medicine
RECRUITINGShibīn al Kawm, Shebin Elkom, 32111, Egypt
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