Mcgill University Health Centre/research Institute Of The Mcgill University Health Centre

This study tests three different catheter ablation techniques in 617 adults with persistent atrial fibrillation (AF) to see which best controls heart rhythm. Participants receive one of three procedures: isolating the pulmonary veins alone, adding ablation of abnormal electrical …

This study gives one child with Cree Leukoencephalopathy (CLE), a severe and fatal brain disease, access to an experimental drug called fosigotifator. The drug aims to slow or stop the breakdown of the brain's white matter. Researchers will monitor if the benefits outweigh the ri…

This study tests a new catheter that combines two types of energy (pulsed field and radiofrequency) to treat ventricular tachycardia, a dangerous fast heart rhythm. About 30 adults with repeated episodes of VT will receive the ablation procedure. The goal is to see if the new too…

This study provides an experimental drug called fosigotifator to one patient with Cree Leukoencephalopathy, a rare and fatal brain disease that currently has no treatments. The drug aims to slow or stop brain damage and improve quality of life. The patient must be in early stages…

This study tests canagliflozin, a drug typically used for diabetes, in people with advanced chronic kidney disease (stages 4 and 5) including those on dialysis. The goal is to see if it safely reduces protein in the urine, a marker of kidney damage, and to measure how the drug be…

This study tests a new wireless sensor that continuously measures the light dose babies receive during phototherapy for jaundice. Current methods only check light levels once a day, which can be less accurate. The goal is to see if these sensors work as well as standard devices t…

This study tests a new, non-invasive acoustic sensor that listens to breathing sounds in premature babies on breathing support. Researchers will enroll 50 preterm infants to see if the sensor can reliably detect breathing problems compared to standard monitors. The goal is to imp…

This study is testing whether wireless, wearable sensors can safely and accurately monitor the heart rate, breathing, temperature, and oxygen levels of newborn babies in the Neonatal Intensive Care Unit (NICU). Researchers will compare the wireless data to standard wired monitors…