Mcgill University Health Centre/research Institute Of The Mcgill University Health Centre
Clinical trials sponsored by Mcgill University Health Centre/research Institute Of The Mcgill University Health Centre, explained in plain language.
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Are cheaper versions of a key vasculitis drug just as safe and effective?
Disease control CompletedThis study looked at 201 Canadian patients with ANCA-associated vasculitis to see if biosimilar versions of rituximab work as well as the original drug. Researchers tracked disease control, side effects, and how long it took to get insurance approval for treatment. The goal is to…
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated May 26, 2026 05:23 UTC
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New weight loss surgery shows promise in study
Disease control CompletedThis study tested a newer, simpler weight loss surgery called SADI-S against a standard, more complex surgery (BPD-DS) in 62 adults with severe obesity. The goal was to see if SADI-S is safer and just as effective for weight loss and related health problems like diabetes. Researc…
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated May 26, 2026 05:22 UTC
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Growth hormone shows promise in shrinking HIV's secret hideout
Disease control CompletedThis study tested whether giving recombinant human growth hormone for 48 weeks could reduce the hidden HIV reservoir in 22 adults already on successful antiretroviral therapy (ART). The goal was to see if this approach could help the immune system naturally control the virus, mov…
Phase: PHASE2 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated May 26, 2026 04:35 UTC
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Could a 2-Month TB prevention be as good as 4 months?
Disease control CompletedThis study tested whether taking a higher dose of the antibiotic rifampin for 2 months is as safe and effective as the standard 4-month treatment for latent tuberculosis (TB). About 1,368 adults and children aged 10 and older with latent TB took part. Participants received either…
Phase: PHASE2 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated May 18, 2026 12:11 UTC
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Virtual fitness and nutrition program aims to keep older men on their feet
Disease control CompletedThis pilot study tested whether a telehealth program combining strength training, balance exercises, and nutrition advice could help older men at high risk for falls and fractures. Forty-five men aged 60 and older participated. The goal was to see if the program was practical and…
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Disease control
Last updated May 13, 2026 16:02 UTC
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Smartwatch could detect heart failure early, study finds
Diagnosis CompletedThis study tested whether a smartwatch can pick up signs of heart failure by tracking body signals like heart rate and movement, and recording voice patterns. Researchers compared 56 people with and without heart failure during physical tasks and daily life. The goal is to find n…
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Diagnosis
Last updated May 26, 2026 05:22 UTC
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Simple taper strategy may cut c. diff recurrence risk
Prevention CompletedThis study looked at whether giving a gradual, lower dose of vancomycin for two extra weeks after the standard treatment can prevent C. diff infection from coming back. About 263 adults who had their first or second C. diff infection took part. Half received a placebo and half re…
Phase: PHASE3 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Prevention
Last updated May 20, 2026 11:53 UTC
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Coaching program boosts Parents' confidence in raising kids with developmental delays
Symptom relief CompletedThis study tested a coaching program for parents of young children (ages 1.5 to 4.5 years) with suspected or confirmed developmental delays. The program included a personal coach, online tools, and a peer support network. Researchers wanted to see if this approach could help pare…
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Symptom relief
Last updated May 26, 2026 05:25 UTC
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Breathing easy: new study reveals best puffers for COPD attacks
Symptom relief CompletedThis study looked at which combination of inhalers works best to open the lungs during a COPD lung attack. 37 people with COPD who were having a lung attack took part. They used a gentle breathing test called oscillometry to measure lung function after different inhaler combinati…
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Symptom relief
Last updated May 26, 2026 04:36 UTC
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Diabetes drug shows promise for fluid removal in tough heart failure cases
Symptom relief CompletedThis study looked at whether adding empagliflozin (a diabetes drug) to standard water pills helps people with acute heart failure and moderate-to-severe kidney disease urinate out more excess fluid. 25 adults participated, and researchers measured urine output after combining the…
Phase: PHASE4 • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Symptom relief
Last updated May 18, 2026 12:13 UTC
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Heart test during surgery may spot deadly risks
Knowledge-focused CompletedThis study tested whether a special heart ultrasound during major surgery can help identify patients at higher risk of dying or having a heart attack afterward. Researchers used a drug to stress the heart and tracked its motion in real time. The goal was to see if this test could…
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Knowledge-focused
Last updated May 26, 2026 05:26 UTC
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Prehab before liver transplant: small study tests exercise, diet, and support
Knowledge-focused CompletedThis study tested whether a structured program combining exercise, nutrition advice, and psychological support is practical and safe for adults with cirrhosis waiting for a liver transplant. 25 participants were enrolled. The goal was to see if patients could stick with the progr…
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Knowledge-focused
Last updated May 26, 2026 05:25 UTC
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New scope method for liver biopsy tested against standard procedure
Knowledge-focused CompletedThis study compared two methods for taking liver tissue samples and measuring blood pressure in the liver: one using an endoscope through the mouth (EUS) and the other using a catheter inserted through a neck vein (transjugular). 58 adults with chronic liver disease or portal hyp…
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Knowledge-focused
Last updated May 26, 2026 04:36 UTC
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Can a smartphone app ease Parents' fears about childhood epilepsy?
Knowledge-focused CompletedThis study tested a mobile app designed to educate parents and caregivers of children with epilepsy. The app provides information about the condition, tracks symptoms, and helps manage appointments. Researchers compared 36 families who used the app with 36 who received standard c…
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC
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Can a Self-Guided online program boost emotional health in families?
Knowledge-focused CompletedThis study tested whether an online, self-guided program called eParenting CARE is practical and helpful for parents of children aged 8 to 13. The program teaches parents skills to manage their own emotions and support their child's emotional well-being. Researchers enrolled 67 p…
Phase: NA • Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Knowledge-focused
Last updated May 14, 2026 12:04 UTC
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Smartwatch AI spots hidden diabetes clues
Knowledge-focused CompletedThis study tested whether a smartwatch could help identify digital signs of type 2 diabetes. Researchers gave 210 adults a special watch to track health data like activity and heart signals. They used artificial intelligence to find patterns linked to diabetes. The goal was to im…
Sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre • Aim: Knowledge-focused
Last updated May 11, 2026 20:51 UTC