Johns Hopkins University
Clinical trials sponsored by Johns Hopkins University, explained in plain language.
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Brain pacemaker tested for uncontrollable tics
Disease control TerminatedThis study tested whether deep brain stimulation (DBS) could help people with severe Tourette syndrome whose symptoms don't improve with medication. Small wires were placed in a part of the brain called the thalamus to try to calm abnormal signals causing tics. Only 2 people took…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated May 22, 2026 14:03 UTC
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Brain pacemaker trial for untreatable schizophrenia shows promise
Disease control TerminatedThis study tested a brain pacemaker (deep brain stimulation) in 15 people with severe schizophrenia that did not improve with standard treatments. The goal was to reduce persistent hallucinations and delusions by targeting a specific brain area. The study was stopped early, but i…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated May 22, 2026 13:52 UTC
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At-Home brain zaps aim to boost thinking in dementia
Symptom relief TerminatedThis study tested whether a non-invasive brain stimulation technique called tDCS, done at home, could improve thinking and language skills in people with primary progressive aphasia, mild cognitive impairment, or dementia. Participants received tDCS paired with computer-based cog…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 26, 2026 02:44 UTC
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COVID-19 drug trial fizzles: only 4 patients enrolled
Symptom relief TerminatedThis study aimed to see if emetine, an older drug, could help adults with mild-to-moderate COVID-19 feel better faster and avoid hospitalization. Participants took emetine pills or a placebo for 10 days. However, the trial was stopped early after enrolling only 4 people, so no me…
Phase: PHASE2, PHASE3 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Brainwave boost: EEG training may ease aphasia symptoms
Symptom relief TerminatedThis study tested whether EEG neurofeedback training—a technique where people learn to control their brainwaves—can improve communication, anxiety, and sleep in adults with aphasia (language loss from stroke or a condition called primary progressive aphasia). Seven participants r…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 22, 2026 13:51 UTC
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Placental wrap fails to prove erection boost in prostate surgery study
Symptom relief TerminatedThis study tested whether placing a special placental tissue over nerves during prostate removal surgery could help men recover erections and bladder control faster. Only 3 men with early-stage prostate cancer took part before the study was stopped early. The approach was experim…
Phase: PHASE2 • Sponsor: Johns Hopkins University • Aim: Symptom relief
Last updated May 22, 2026 13:50 UTC
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Empowerment through wellness: a program for survivors of domestic violence
Knowledge-focused TerminatedThis study aimed to help women living in emergency shelters after experiencing intimate partner violence. Ten women took part in group sessions that included mindfulness exercises and health education to improve their physical and emotional well-being. The program was designed to…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 26, 2026 02:52 UTC
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Ultrasound watch for skin cancer spread shows promise
Knowledge-focused TerminatedThis study looked at whether regular ultrasound scans of lymph nodes could find cancer spread earlier in people with high-risk skin cancer on the head or neck. The study planned to include patients with certain high-risk features, but only one person enrolled before it was stoppe…
Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated May 26, 2026 02:42 UTC