Jaeb Center For Health Research

This study is testing an automated insulin delivery system, called the bionic pancreas, for people with diabetes caused by cystic fibrosis. It will compare the device against participants' usual insulin methods over 13 weeks to see if it helps keep blood sugar in a healthy range …

This study is testing if using a home scanner to check the eye daily can help doctors give fewer eye injections while keeping vision just as good for people with 'wet' age-related macular degeneration (AMD). It compares this new home-monitoring approach to the current standard 't…

This study is testing whether two different video-based therapies are better than glasses alone at improving vision in children aged 8 to 12 with amblyopia, often called 'lazy eye.' Children will be randomly assigned to use either a movie-based system, a game-based system, or to …

This study is testing whether using inhaled insulin before a meal is safer than using insulin from a pump when people with type 1 diabetes exercise after eating. Researchers want to see which method better prevents dangerous drops in blood sugar during exercise. About 30 adults w…

This study aims to determine the best timing for surgery to remove epiretinal membranes, which are thin scar tissues on the eye's retina that can cause vision distortion. Researchers will compare immediate surgery against waiting until vision worsens to see which approach leads t…

This study is testing if two different eye injections can prevent long-term vision loss in people who received radiation treatment for a type of eye cancer called choroidal melanoma. The trial will compare the injections against simply monitoring vision and only treating if probl…

This study compares two common treatment approaches for lazy eye (amblyopia) in children ages 3-13. Researchers want to know if starting with glasses alone and adding an eye patch only if needed works as well as using glasses and an eye patch together from the beginning. The tria…

This study is comparing two different approaches to treat a serious eye complication of diabetes called proliferative diabetic retinopathy (PDR). It will test whether a series of eye injections combined with laser therapy works as well as or better than a single eye surgery. Rese…

This study compares two treatments for lazy eye (amblyopia) in children ages 4-7. Researchers want to see if watching special movies through a headset for 1 hour daily works as well as wearing an eye patch for 2 hours daily. The study will follow 238 children for 26 weeks to meas…

This study is testing if a pill called fenofibrate can prevent mild to moderate diabetic eye disease from getting worse. It will involve 560 adults with diabetes and early-stage eye changes, who will take either fenofibrate or a placebo for up to 6 years. The goal is to see if th…

This study is testing if using a continuous glucose monitor (CGM) early in pregnancy can help find and manage high blood sugar sooner than usual care. It aims to see if this early detection prevents problems like having a very large baby, birth injuries, or high blood pressure in…

This study aims to understand how common diabetes-related complications are in people with cystic fibrosis who have had diabetes for at least five years. Researchers will examine 200 adolescents and adults to check for eye, kidney, and nerve problems, as well as heart disease ris…

This study aims to build a detailed registry and track the natural progression of rare genetic eye diseases that cause vision loss, like retinitis pigmentosa. It will follow 1,500 participants worldwide who have specific rare genetic variants to understand how their vision change…