Jaeb Center For Health Research

This study tests whether playing special video games or watching movies through a virtual reality headset can improve vision in children aged 8 to 12 with amblyopia (lazy eye). About 252 kids will be randomly assigned to one of three groups: VR games, VR movies, or just wearing g…

This study tests two treatments to slow the progression of myopia (nearsightedness) in children aged 5 to 12. One treatment is a daily eye drop with a low dose of atropine, and the other is a special type of eyeglass lens. The trial will include 348 children and follow them for 2…

This study tests whether watching specially designed movies through a virtual reality headset for 1 hour a day can improve vision in children with amblyopia (lazy eye) as effectively as the standard treatment of wearing an eye patch for 2 hours a day. The trial involves 238 child…

This study tests two ways to treat proliferative diabetic retinopathy, a serious eye problem caused by diabetes. One group gets eye injections of faricimab plus laser treatment; the other gets vitrectomy surgery with laser. Researchers will track vision and how many extra treatme…

This study tests whether two different eye treatments can prevent vision loss in people who have had radiation therapy for a type of eye cancer called uveal melanoma. The treatments are faricimab injections every 3 months or a fluocinolone acetonide implant placed in the eye. 600…

This study looks at the best way to treat lazy eye (amblyopia) in children aged 3 to under 13. Some children get glasses and an eye patch at the same time, while others start with glasses alone and add patching later if needed. The goal is to see if both approaches lead to simila…

This study looks at whether inhaled insulin (Afrezza) is safer than standard pump insulin for preventing low blood sugar during exercise after a meal. About 30 adults with type 1 diabetes who use a Tandem pump with Control-IQ will complete three exercise sessions in a clinic. The…

This study tests whether daily home eye scans can guide when to give injections for wet age-related macular degeneration, compared to the standard treat-and-extend schedule. Six hundred adults aged 50 and older with wet AMD will use a home OCT device daily for two years. The goal…

This study tests whether wearing a continuous glucose monitor (CGM) early in pregnancy can quickly detect and manage high blood sugar in 6,000 pregnant women. The goal is to reduce serious problems for the baby (like being too large, birth injuries, or NICU stays) and for the mot…

This study tests a smart insulin pump called the iLet Bionic Pancreas in 150 people aged 14 and older with cystic fibrosis-related diabetes. The pump automatically adjusts insulin based on continuous glucose monitor readings. Participants are randomly assigned to use the bionic p…

This study tests whether fenofibrate, a drug already used for high cholesterol, can prevent diabetic retinopathy from worsening in people with mild to moderate disease. About 560 adults with diabetes will take either fenofibrate or a placebo for up to 6 years. The goal is to see …

This study is observing 300 children under 18 with uveitis, an eye inflammation condition. Researchers want to learn how common different types of uveitis are and what treatments children receive. Participants have one visit with their doctor, and some will have their medical rec…

This international study will enroll 1,500 people with rare inherited retinal diseases like retinitis pigmentosa. Researchers will collect genetic and vision data over time to learn how these conditions progress. The goal is to build a foundation for future treatments, not to tes…

This study looks at how often people with cystic fibrosis and diabetes develop complications like eye, kidney, and nerve problems. Researchers will also check blood pressure and cholesterol. The goal is to better understand these risks in a diverse group of 200 adolescents and ad…

This study compares immediate surgery versus waiting for vision to worsen in people with an epiretinal membrane (a thin layer of scar tissue on the eye's surface). It includes 400 adults with relatively good vision (20/40 or better) who have symptoms like blurring or distortion. …