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Can special lenses or drops stop Kids' eyesight from worsening?

NCT ID NCT07095894

First seen Jun 24, 2026 · Last updated Jun 24, 2026

Summary

This study tests two treatments to slow the progression of myopia (nearsightedness) in children aged 5 to 12. One treatment is a daily eye drop with a low dose of atropine, and the other is a special type of eyeglass lens. The trial will include 348 children and follow them for 2 years to see if these treatments reduce eye growth and prescription changes.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ann & Robert H. Lurie Children's Hospital of Chicago

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Boston Children's Hospital Waltham

    RECRUITING

    Boston, Massachusetts, 02453, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Casey Eye Institute

    RECRUITING

    Portland, Oregon, 97239, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Eye Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Email: •••••@•••••

  • Illinois College of Optometry

    RECRUITING

    Chicago, Illinois, 60616, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Marshall B. Ketchum University

    RECRUITING

    Fullerton, California, 92831, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ohio State University College of Optometry

    RECRUITING

    Columbus, Ohio, 43210-1280, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Pediatric Ophthalmology Associates, Inc.

    RECRUITING

    Columbus, Ohio, 43205, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Stanford University

    RECRUITING

    Palo Alto, California, 94303, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • UAB Pediatric Eye Care; Birmingham Health Care

    RECRUITING

    Birmingham, Alabama, 35294, United States

  • University of Houston - College of Optometry

    RECRUITING

    Houston, Texas, 77204, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Vanderbilt University Medical Center - Vanderbilt Eye Institute

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

0.05% atropine eyedrops and spectacle lenses with highly aspherical lenslets (HAL)

What this could lead to

If successful, this could provide effective, non-surgical options to slow worsening nearsightedness in children, reducing the need for stronger prescriptions and lowering long-term eye health risks.

What could go wrong

This is a Phase 3 trial, but previous results in non-Asian children have been inconsistent. The treatments may not work as well in this broader population, and atropine drops can cause side effects like light sensitivity or blurred near vision.

Conditions

The condition(s) this trial relates to.

myopia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.