Istituto Ortopedico Rizzoli
Clinical trials sponsored by Istituto Ortopedico Rizzoli, explained in plain language.
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Could your own fat cells heal a painful knee tendon?
Disease control CompletedThis study tested whether injecting a patient's own fat-derived cells (stromal vascular fraction) into the damaged knee tendon could improve symptoms of patellar tendinopathy (jumper's knee). Thirty adults with tendon damage seen on ultrasound or MRI received the injection. The m…
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated May 26, 2026 04:44 UTC
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Spine surgery showdown: which fix keeps teens moving best?
Disease control CompletedThis study looked at two types of surgery for teens with curved spines (scoliosis): vertebral body tethering (VBT) and posterior spinal fusion (PSF). The goal was to see which one corrects the curve better and keeps the spine flexible during movement. Researchers followed 12 teen…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated May 26, 2026 04:36 UTC
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New shoulder surgery without implants shows promise in small pilot study
Disease control CompletedThis pilot study tested a surgical technique using an implant-free bone graft to treat anterior shoulder dislocation with bone loss. Twenty patients were evaluated for safety and improvement in shoulder function over 24 months using the DASH questionnaire. The goal was to see if …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated May 26, 2026 04:34 UTC
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New ACL graft material shows promise in small trial
Disease control CompletedThis study tested a new material called OrthoPure XT for repairing torn knee ligaments (ACL) in 10 people. Researchers measured pain, knee function, and activity levels using surveys and MRI scans. The goal was to see if the material works well for patients who cannot use their o…
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Disease control
Last updated May 26, 2026 04:31 UTC
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Blood biomarkers could revolutionize scoliosis diagnosis
Diagnosis CompletedThis study looked at tiny molecules called microRNAs in the blood of 20 teens with scoliosis and 10 healthy teens. The goal was to find patterns that could help diagnose scoliosis earlier and more easily. If successful, this could lead to a simple blood test instead of relying on…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Diagnosis
Last updated May 26, 2026 04:31 UTC
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Fat cell injection shows promise for hip arthritis pain relief
Symptom relief CompletedThis study tested whether injecting a person's own fat tissue into the hip joint can safely reduce pain and improve movement in hip osteoarthritis. Thirty adults aged 40 to 70 with mild to moderate hip arthritis received one ultrasound-guided injection. Researchers tracked pain, …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Symptom relief
Last updated May 26, 2026 04:34 UTC
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Hidden nerve pinch may be key to beating stubborn low back pain
Symptom relief CompletedThis study tested a treatment for a condition called superior cluneal nerve entrapment, where a nerve in the lower back gets pinched and causes pain. 41 adults with this nerve problem received treatment to release the nerve. The goal was to reduce their low back pain and improve …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Symptom relief
Last updated May 26, 2026 04:31 UTC
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New pain block may cut opioid use in teen scoliosis surgery
Symptom relief CompletedThis study tested whether an ultrasound-guided nerve block (ESP block) given before spinal surgery for scoliosis can lower pain and the need for strong painkillers in teenagers. Eleven adolescents took part, with half receiving the block plus general anesthesia and half receiving…
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Symptom relief
Last updated May 22, 2026 13:55 UTC
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New Mini-Invasive spine surgery shows promise for severe scoliosis
Symptom relief CompletedThis study tested a less invasive surgery to correct severe spine curvature in people with neuromuscular scoliosis, a condition linked to nerve or muscle problems. The goal was to see if the mini-invasive approach could reduce pain, improve spine alignment, and lower complication…
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Symptom relief
Last updated May 22, 2026 13:53 UTC
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Knee pain relief shot tested in small pilot study
Symptom relief CompletedThis study tested whether an ultrasound-guided injection of triamcinolone (a steroid) and lidocaine (a numbing agent) can reduce pain and improve knee function in people with medial plica syndrome that did not get better with other treatments. 30 adults with confirmed medial plic…
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Symptom relief
Last updated May 19, 2026 11:59 UTC
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Sailing therapy sets sail for rare bone disorder rehab
Symptom relief CompletedThis study tested whether combining a 5-day sailing therapy program with a 3-month home telerehabilitation plan is safe and doable for 24 young people (ages 12–30) with rare skeletal disorders. Participants were randomly assigned to either the sailing-plus-telerehab group or a te…
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Symptom relief
Last updated Apr 30, 2026 15:50 UTC
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Brittle bone breakthrough? new study tracks movement to unlock disease secrets
Knowledge-focused CompletedThis study aimed to better understand osteogenesis imperfecta (brittle bone disease) by collecting information from 33 patients. Researchers used special sensors to analyze how patients walk and move, and also looked at their genetic data and quality of life. The goal was to gath…
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 26, 2026 04:43 UTC
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Do flat feet or knock knees delay motor skills? new study investigates
Knowledge-focused CompletedThis study looked at 151 children with common postural variations like flat feet, knock knees, or scoliosis to see if these conditions affect motor control. Researchers used wearable motion sensors and simple clinical tests to measure balance and movement skills. The goal was to …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 26, 2026 04:36 UTC
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Ankle fracture surgery under the microscope: what really happens after?
Knowledge-focused CompletedThis study looked back at the medical records of 107 people who had surgery for a broken ankle bone (the fibula) to see how well they healed and what problems they had. The goal was to understand recovery times and functional outcomes using standard questionnaires. No new treatme…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 26, 2026 04:35 UTC
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Scientists analyze genetic markers in stored samples to advance personalized medicine
Knowledge-focused CompletedThis completed study looked at DNA methylation patterns in samples from 90 patients with rare skeletal disorders, sarcomas, or inflammatory arthritis. The goal was to better understand these diseases and improve how biobank data is shared for future research. No new treatments we…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 26, 2026 04:32 UTC
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Healthy knees run cool: new study maps normal temperature zones
Knowledge-focused CompletedThis study looked at 60 healthy volunteers aged 18 to 35 to measure the normal temperature of different parts of the knee using a special camera that detects heat (thermography). The goal was to create a set of normal temperature values that doctors can use as a reference. Resear…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 26, 2026 04:32 UTC
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Leg cancer surgery recovery tracked in new study
Knowledge-focused CompletedThis study followed 100 cancer patients who had surgery to remove and rebuild part of their lower leg or pelvis. Researchers measured how independent patients became in daily activities and how well their joints moved during the first six months after surgery. The goal was to und…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 26, 2026 04:30 UTC
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Skipping surgery for a torn biceps? new study says it might be an option
Knowledge-focused CompletedThis study looked at 30 adults who had a complete tear of the lower biceps tendon but chose not to have surgery. After at least one year, researchers measured their elbow function, arm strength, and fatigue using standard tests and compared the injured arm to the healthy one. The…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 22, 2026 13:55 UTC
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Spine surgery movement study: a closer look at recovery
Knowledge-focused CompletedThis study looked at how spine surgery for tumors changes the way people move. Ten adults with spinal cancer had their walking and trunk movements measured before and after surgery. The goal was to learn more about recovery and improve future treatments.
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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Simple balance tests may predict fall risk after joint replacement
Knowledge-focused CompletedThis study looked at whether simple balance and movement tests can predict which patients are likely to fall after hip or knee replacement surgery. Researchers tested 200 patients before their operation using tools like the Timed Up and Go test and a step test. They then tracked …
Phase: NA • Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC
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Scientists dig into Tumor's immune secrets to improve osteosarcoma knowledge
Knowledge-focused CompletedThis study looked at tumor samples from 80 people with localized osteosarcoma who had already received chemotherapy with or without a drug called mifamurtide. Researchers analyzed 770 genes related to the immune system to see how the tumor's environment affects survival. The goal…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 18, 2026 12:01 UTC
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Knee surgery outcomes under review: hope for complex ligament injuries
Knowledge-focused CompletedThis study looked at 42 people who had surgery for multiple torn knee ligaments, often from high-energy accidents. Researchers measured knee function and symptoms using standard scores to see how well patients did over the long term. The goal was to gather information to help doc…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC
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Knee scaffold treatment: what happens after surgery?
Knowledge-focused CompletedThis study followed 41 people who had a scaffold implanted to treat partial meniscus tears in the knee. Researchers collected data from medical records and phone interviews to see how patients' pain, knee function, and quality of life changed over time. The goal was to understand…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated May 07, 2026 18:39 UTC