Istituto Clinico Humanitas

This study tests whether adding a precise, high-dose type of radiation (stereotactic body radiation therapy, or SBRT) to standard treatments like chemotherapy or immunotherapy can better control bladder cancer that has spread to a limited number of places (up to 3 spots). The tri…

This study tests whether giving focused radiation before surgery for large brain metastases (tumors that spread from other cancers) works better than radiation after surgery. About 146 adults with 1-4 brain tumors will be randomly assigned to one of the two timing schedules. The …

This study looks at using a special type of radiation (SBRT) to treat kidney cancer in people who cannot have surgery due to health risks or personal choice. The treatment delivers high doses of radiation in just a few sessions, is non-invasive, and does not require anesthesia or…

This study tests new rapid tests that identify which antibiotics will work against bloodstream infections, compared to standard slower tests. The goal is to help doctors prescribe the right antibiotic sooner, improving patient outcomes and reducing unnecessary broad-spectrum drug…

This study looks at 30 adults with acute respiratory failure who need a breathing machine. Doctors already use two methods to set the machine's pressure: a lung CT scan (which involves radiation and moving the patient) and a safer, simpler device called electrical impedance tomog…

This study looks at using a very precise type of radiation (SBRT) a second time for lung cancer patients whose tumor has returned in the same spot. It includes 150 people who cannot have surgery and have already had SBRT once. The goal is to learn how safe and effective this seco…

This study looks at whether a precise type of radiation called SBRT can help control breast cancer that has spread to only a few other parts of the body. Researchers will review medical records from 300 patients to see if SBRT improves how long they live without the disease getti…

This study investigates whether serious muscle weakness, known to affect ICU patients, also occurs in those hospitalized outside the ICU. Researchers will follow 600 adults in non-ICU wards, half with organ failure and half without, to track how often weakness develops and what f…

This study is collecting information from 500 adults with solid tumors who are receiving proton therapy, a type of radiation that may cause fewer side effects than standard radiation. The goal is to gather real-world data on how well proton therapy controls cancer and its side ef…