Istituti Clinici Scientifici Maugeri Spa

This study is testing if a gentle, non-invasive stimulation of a nerve in the ear can help people recover arm movement after a stroke. It will involve 48 stroke survivors who are already in rehab. They will try the ear stimulation along with their regular therapy to see if it hel…

This study is testing whether a high-tech rehabilitation program is better than standard rehab for adults recovering from sudden, severe nerve and muscle diseases like Guillain-Barré Syndrome. Researchers will compare a group using robotic systems, virtual reality, and balance pl…

This study is testing a new artificial intelligence (AI) system designed to help doctors diagnose celiac disease and similar gut conditions. The AI is trained to spot signs of intestinal damage in images from endoscopy procedures. Researchers will compare how accurately the AI an…

This study is testing a new device that uses light and artificial intelligence to help surgeons check if all cancer has been removed during breast-conserving surgery. The device scans the removed tissue during the operation and quickly identifies areas where cancer cells might re…

This study is testing a new device designed to find and analyze individual cancer cells in the blood of people with breast cancer. The goal is to see if this 'liquid biopsy' can help doctors better understand a patient's cancer and guide treatment decisions. The study will enroll…

This study is testing if a high-intensity strength training program is easier to tolerate and more effective than traditional endurance training for people recovering from a COPD flare-up. It will involve 64 participants who were recently hospitalized for COPD. The main goal is t…

This study is testing if adding a special type of musical feedback, called 'sonification,' to standard walking therapy can help people walk better. It will involve 120 people with Parkinson's disease, multiple sclerosis, or who have had a stroke. One group will get standard thera…

This study is testing a new rehabilitation method for adults recovering from traumatic brain injury (TBI). Researchers want to see if wearing special prism lenses that shift vision, combined with playing targeted computer games, can improve thinking skills like memory and attenti…

This study is testing whether special prism glasses, combined with a gentle form of brain stimulation, can help stroke patients who have 'neglect'—a condition where they have trouble noticing things on one side of their body or environment. It will compare the glasses plus real b…

This study is testing if a specific type of heavy weight training can help people with COPD feel better in their daily lives. It will compare this strength training to standard endurance exercise in 20 participants. The main goal is to see if lifting heavy weights improves walkin…

This study is testing personalized speech and language therapy for people with primary progressive aphasia (PPA), a brain condition that gradually impairs speech and communication. Researchers will work with 30 patients to develop therapy plans tailored to their specific language…

This study is testing whether adding two dietary supplements, L-arginine and vitamin C, to a standard 28-day lung rehabilitation program can help reduce severe fatigue in people with COPD and chronic breathing failure. About 102 participants will be randomly assigned to receive e…

This study is testing whether listening to personalized music daily can help reduce anxiety and depression in people recovering from a recent stroke. About 132 participants will be randomly assigned to either receive standard care plus four weeks of daily music listening sessions…

This study aims to help people adjust after a leg amputation, often caused by diabetes. It will compare standard rehabilitation to a program that adds technology like virtual reality. Researchers want to see which approach better improves daily function, reduces pain and fall ris…

This study is testing if adding music to standard rehabilitation training helps people with COPD and chronic breathing problems. Researchers want to see if listening to music during exercise helps patients walk farther, feel less shortness of breath, and get less tired. They will…

This study is testing a personalized, non-invasive brain stimulation technique to see if it can help reduce chronic pain. Researchers will recruit 144 adults with long-term pain that hasn't responded well to other treatments. Participants will receive either real or placebo stimu…

This study aims to find better ways to spot Alzheimer's disease in its earliest stages. Researchers will study 80 people with memory concerns and their caregivers, combining blood tests, brain scans, and questionnaires. The goal is to understand how biological, psychological, and…

This study aims to better understand the thinking patterns and brain activity in people with different eating disorders. Researchers will compare adults with ARFID, anorexia, bulimia, and healthy volunteers. Participants will complete questionnaires and computer tasks to measure …

This study aims to understand how damage to specific brain areas affects a person's ability to mentally travel in time—to remember past events and imagine future ones. Researchers will recruit 66 people with focal brain injuries to see if thinking about themselves versus others c…

This study aims to create and test an Italian version of a questionnaire that measures how much chronic low back pain affects people's daily lives. Researchers will work with 115 Italian-speaking adults who have had back pain for at least three months. Participants will complete …

This study aims to better understand how hereditary angioedema affects patients' daily lives by tracking their experiences in real time. Over 8 weeks, 30 adult participants will use their smartphones to answer brief daily surveys about their mood, stress, and how the disease impa…

This study aims to understand why many people with obstructive sleep apnea don't use their CPAP machine consistently, which is the best treatment. Researchers will test if a person's decision-making style, specifically how they weigh effort versus reward, predicts poor adherence.…

This study is testing a new, highly sensitive blood test method to detect tiny particles released by breast cancer cells. Researchers will compare blood samples from 105 women with early-stage breast cancer, metastatic breast cancer, and healthy volunteers. The goal is to see if …

This study aims to collect tumor samples from 240 breast cancer patients before they start chemotherapy. Researchers will use these samples to grow miniature 3D tumor models called organoids in the lab. By studying these organoids and tiny particles they release, the study hopes …