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Music may boost COPD rehab: study tests tunes for better breathing

NCT ID NCT05720780

Symptom relief Sponsor: Istituti Clinici Scientifici Maugeri SpA Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether adding music to standard exercise training helps people with COPD and chronic respiratory failure improve their walking distance and feel less breathless. 156 participants will either do usual rehab or rehab while listening to music they choose (rock, modern, jazz, or classical). The main goal is to see if more people in the music group can walk at least 30 meters farther in a six-minute walk test.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
music listening during exercise training
What this could lead to
If it works, this could offer a simple, enjoyable way to improve exercise capacity and reduce breathlessness in people with COPD.
What could go wrong
This is a small, early-stage trial with no blinding, so results may be influenced by placebo effects. The benefit may be modest and not apply to all COPD patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 156 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2023

Expected to finish

Apr 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

40 to 85 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of COPD (Forced expiratory volume in 1 second / post-bronchodilator forced vital capacity \< 0.7) without functional reversibility * Chronic respiratory failure with stable hypoxia (PaO2 \< 60 mmHg in room air) * Long Term Oxygen Therapy (LTOT) for at least 3 months * Clinical stability: pH range 7.38-7.42, with no recent exacerbations in the last 7 days and no changes in drug therapy in the previous 7 days Exclusion Criteria: * Non-invasive ventilation at home * Cognitive impairment (Mini-Mental State Examination Score \< 22) * Asthma or evidence of bronchodilator response * Pulmonary fibrosis * Obstructive sleep apnea syndrome * Lung cancer * Active microbial infections * Neuromuscular, orthopedic, and/or medical conditions that preclude testing * Pulmonary rehabilitation program in the previous 6 months

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Conditions

The condition(s) this trial relates to.

chronic obstructive pulmonary disease COPD, severe early onset respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COPD

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    6 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Lumezzane

    RECRUITING

    Lumezzane, Brescia, 25065, Italy

  • ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Pavia

    RECRUITING

    Pavia, 27100, Italy

  • ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Tradate

    RECRUITING

    Tradate, Varese, 21049, Italy

  • ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Bari

    NOT_YET_RECRUITING

    Bari, 70100, Italy

  • ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Montescano

    RECRUITING

    Montescano, Pavia, 27040, Italy

  • ICS Maugeri IRCCS, respiratory rehabilitation of the Institute of Telese

    NOT_YET_RECRUITING

    Telese Terme, Benevento, 82037, Italy

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