Arm and leg workout combo may ease daily struggles for COPD patients
NCT ID NCT05708443
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether combining arm and leg endurance training is better than leg training alone for improving daily activities in people with COPD. 36 participants with moderate-to-severe COPD will undergo 14 supervised sessions. The main goal is to see if the combined training reduces the time needed to complete a daily task test (GLITTRE test).
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- exercise training (combined upper and lower extremity endurance training vs lower extremity training alone)
- What this could lead to
- If it works, this could show that adding arm exercises to standard leg training helps people with COPD do daily activities more easily.
- What could go wrong
- This is a small, early-stage trial with only 36 participants, so results may not apply to all COPD patients. The benefit of adding arm training may be small or not significant.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 36 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2023
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * GOLD class 2-3 COPD * Forced Expiratory Volume in the first second (FEV1) between 30% and 70% of the predicted value * ability to walk and climb stairs without assistance * stable clinical condition (pH \> 7.35) Exclusion Criteria: * chronic respiratory insufficiency on long-term oxygen therapy (LTOT) * severe orthopedic, neurological or cardiological comorbidities * cognitive impairment * recent exacerbation (within 15 days) requiring a change in therapy * presence of lung disease other than COPD * terminality
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Lumezzane
RECRUITINGLumezzane, Brescia, 25065, Italy
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ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Montescano
NOT_YET_RECRUITINGMontescano, Pavia, 27040, Italy
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ICS Maugeri IRCCS, Respiratory rehabilitation of the Institute of Tradate
COMPLETEDTradate, Varese, 21049, Italy
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