Irccs Azienda Ospedaliero-universitaria Di Bologna

This study compares two medical devices used to recondition lungs from marginal donors before transplantation. About 20 adults needing a double lung transplant will take part. The goal is to see which device helps more donor lungs become suitable for transplant and improves patie…

This study tests whether using a laser to clear re-narrowed heart stents works better than standard balloon treatment. About 1,260 adults with drug-eluting stent restenosis will be randomly assigned to one of the two methods. The main goal is to see which approach reduces heart-r…

This study aims to find out if a newer type of pacemaker, called conduction system pacing, is better than the standard pacemaker at preventing heart failure in people with heart block. About 1,260 adults who need a pacemaker will be randomly assigned to one of the two methods. Re…

This study looks at whether measuring two substances in the blood, called IL-18 and IL-18BP, can help doctors tell apart different causes of fever in children. It will involve 9 children aged 2 to 18 who have conditions like juvenile arthritis, autoinflammatory diseases, or serio…

This study will test whether a new molecular test (RT-PCR) can diagnose Rickettsia infections earlier than current methods. Researchers will study 800 people with suspected infection, using blood and tissue samples already collected during routine care. The goal is to see if the …

This study tests a special wearable device on 5,000 newborns to catch early warning signs of sudden unexpected postnatal collapse (SUPC). The device monitors heart rate and breathing continuously during the first 72 hours of life. The goal is to detect problems early so doctors c…

This international study will collect data from 2000 adults having colorectal surgery with the Hugo RAS robotic system. Researchers will track complications, recovery times, and long-term outcomes like cancer recurrence and bowel function. The goal is to gather real-world evidenc…

This study follows 300 children who had cancer to see how stem cell transplants before puberty affect their final height and hormone levels. Researchers compare those who received a transplant with those who did not. The goal is to understand the long-term impact on growth and pu…

This study aims to understand why some high-grade ovarian cancers do not respond well to standard chemotherapy. Researchers will use a special device called a U-Cup bioreactor to test tumor tissue from 120 women before they start treatment. The goal is to predict which patients w…

This study looks at why some head and neck cancers become resistant to standard therapy. Researchers will collect tumor and blood samples from 120 patients to create lab-grown tumor models in mice. They will also analyze samples from past patients to identify new drug targets tha…

This study watches surgeons as they operate to see how much physical strain they experience. Ten experienced surgeons will wear motion-capture suits and muscle sensors during bowel or prostate surgery using different methods (standard keyhole or robotic systems). The goal is to f…