Irccs Azienda Ospedaliero-universitaria Di Bologna

This study is testing two different medical devices that are used to prepare and improve lungs from 'marginal' donors—those that are not ideal but could still be used—before a transplant. The goal is to see which machine helps get more of these lungs accepted for surgery. Researc…

This study aims to see if a newer, more natural way of pacing the heart (conduction system pacing) is better than the standard method at preventing heart failure events in people with a common heart rhythm problem called atrioventricular block. It will involve 1,260 adults who ne…

This study aims to find a better way to treat reblocked heart stents, a common problem where a previously placed stent narrows again. It will compare a laser-based procedure (ELCA) against standard balloon treatments in 1,260 patients to see which one is more effective at prevent…

This study aims to see if measuring two specific proteins in the blood (IL-18 and IL-18BP) can help doctors tell the difference between rare, serious childhood inflammatory diseases like systemic juvenile idiopathic arthritis and other illnesses that cause fever. Researchers will…

This study is testing a new laboratory method (called RT-PCR) to see if it can diagnose Rickettsia infections, like those from tick bites, more quickly and accurately than current tests. It will involve about 800 people who doctors already suspect have the infection, using sample…

This study is testing a soft, wearable monitor on 5,000 healthy newborns to see if it can spot early warning signs of a rare but dangerous event called sudden unexpected postnatal collapse (SUPC). The device tracks the baby's heart rate and breathing during the first 2-3 days of …

This study aims to understand the physical strain surgeons experience during operations. Researchers will measure muscle activity, posture, and hand forces while surgeons perform procedures using both robotic systems and traditional laparoscopic methods. The goal is to gather dat…

This study aims to understand how a specific cancer treatment affects children's growth and hormone development as they become teenagers and adults. Researchers will compare 300 former pediatric cancer patients: one group had a stem cell transplant before puberty, and the other g…

This study looks back at medical information from 600 people with multiple myeloma who were treated at a hospital in Bologna. Researchers will use computer programs (AI) to analyze their old genetic, imaging, and treatment data to find patterns. The goal is to learn how to better…

This study aims to test a special lab device called the U-Cup bioreactor to see if it can predict whether a patient's ovarian cancer will respond to standard chemotherapy. Researchers will enroll 120 women newly diagnosed with high-grade serous ovarian cancer who have not yet had…

This study aims to understand why some head and neck cancers become resistant to standard treatments. Researchers will analyze tumor samples from 120 patients to identify biological changes that cause treatment resistance. By studying these samples, they hope to find new targets …