Institut Du Cancer De Montpellier - Val D'aurelle

This study is for people with locally advanced rectal cancer. It tests whether using MRI scans early after chemotherapy can help doctors choose the best next step: surgery or more chemo with radiation. The goal is to improve cancer control and reduce side effects. About 1,075 par…

This study is for people with intestinal neuroendocrine tumors that have started growing again after initial treatment with Lutathera. It compares giving two more cycles of Lutathera versus simply monitoring the tumor over six months. The goal is to see if extra treatment can bet…

This study tests whether giving two different chemotherapy combinations one after the other works better than the standard single combination for people with metastatic pancreatic cancer. About 162 adults aged 18 to 75 with confirmed disease will be randomly assigned to either th…

This study is testing whether personalizing the dose and schedule of radiation therapy after breast cancer surgery can reduce long-term side effects like scarring (fibrosis) and radiation-induced cancers, while still preventing the cancer from coming back. The trial will enroll 8…

This study tests whether a special vacuum dressing (negative pressure therapy) can reduce wound complications like infection, reopening, or slow healing after complex breast cancer surgery with reconstruction. About 254 women with risk factors like obesity or smoking will be rand…

This phase 2 trial tests a two-step approach for people with locally advanced pancreatic cancer that cannot be removed by surgery. First, patients receive two powerful chemotherapy regimens in sequence (GEMBRAX then FOLFIRINOX). Then, those whose cancer does not worsen get MRI-gu…

This study is testing whether chemical marks on RNA molecules found in blood and urine can help diagnose gliomas, a type of brain tumor. Researchers will collect samples from 228 adults scheduled for brain surgery and compare them to healthy controls. The goal is to develop a non…

This study is testing a blood test called NovaGray RILA Breast® to see if it can predict severe capsular contracture (hardening and tightening of scar tissue around a breast implant) after radiotherapy. Researchers will enroll 250 breast cancer patients who have had a mastectomy …

This study tests whether doing physiotherapy and using a mechanical stimulation device before breast reconstruction surgery can reduce shoulder pain and improve movement afterward. About 72 women scheduled for a specific type of breast reconstruction (using a back muscle flap) wi…

This study tests whether shining a special laser light on painful areas can reduce nerve pain caused by chemotherapy. About 70 cancer survivors with lasting nerve pain will receive either real or placebo laser treatments. The goal is to see if this safe, non-drug approach can imp…

This study tests whether a program combining physical therapy, yoga, and patient education can reduce joint and muscle pain caused by hormone therapy in breast cancer patients. About 108 women with non-metastatic breast cancer and moderate-to-severe pain will be randomly assigned…

This study tests whether adding music therapy to standard smoking cessation support helps cancer patients quit. 26 participants will work with a music therapist to create a personalized soundtrack to manage withdrawal symptoms and cravings. The goal is to see if this combined app…

This study tests a new type of radiation therapy that adapts to changes in the body during treatment, aiming to reduce side effects like skin burns and scarring. It includes 500 women with breast cancer who are at high risk of fibrosis (hardening of breast tissue). The goal is to…

This study tracks quality of life in 190 people with inoperable lung tumors or up to 3 lung metastases who receive a single high-dose radiation treatment. Participants fill out questionnaires before treatment and at several points over a year to measure symptoms like breathing tr…

This study tests whether a daily breathing exercise called cardiac coherence can lower anxiety in people awaiting surgery for peritoneal cancer. About 60 participants will either practice the technique or receive standard care. The goal is to see if this simple, drug-free method …

This study tests a remote cognitive rehabilitation program for adults with slow-growing brain tumors (grade 2 or 3 glioma) who often struggle with memory, attention, and thinking. About 187 participants will either receive the program or standard care. The goal is to see if the p…

This study aims to understand how a light-based treatment called photobiomodulation affects sexual quality of life in women with breast cancer who have menopausal symptoms like vaginal dryness and pain. About 25 women will be asked about their sexual health before and after the t…

This study compares two approaches to sexual health support for breast cancer patients who recently finished standard treatment. One group gets personalized, proactive care, while the other gets support only when they ask. Researchers will measure sexual quality of life over two …

This study is creating a large database of medical information and blood samples from 350 adults receiving metabolic radiotherapy for thyroid, prostate, or neuroendocrine cancers. The goal is to provide researchers with valuable data to better understand these treatments. No new …

This study looks at whether preserving the left colic artery during colon or rectal cancer surgery helps keep the remaining colon well-supplied with blood. Surgeons will temporarily clamp the main artery and use a green dye to measure blood flow. The goal is to see if this techni…

This study looks at what motivates people aged 70 and older with cancer to be physically active and eat healthy. Researchers will group participants based on their motivation patterns, then test a personalized program to help them improve their activity and diet. The goal is to d…

This study is testing whether women with early-stage luminal breast cancer can follow a special diet (ketogenic or protein-restricted) for about 9 days before their surgery. The main goal is to see if patients can stick to the diet. Researchers will also look at how the diet affe…