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Can a vacuum dressing stop wound infections after breast cancer surgery?

NCT ID NCT06265558

First seen Nov 17, 2025 · Last updated Jun 23, 2026 · Updated 24 times

Summary

This study tests whether a special vacuum dressing (negative pressure therapy) can reduce wound complications like infection, reopening, or slow healing after complex breast cancer surgery with reconstruction. About 254 women with risk factors like obesity or smoking will be randomly assigned to get either the vacuum dressing or a standard dressing. The goal is to see if the vacuum dressing leads to fewer wound problems within 30 days after surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Centre Georges-François Leclerc

    NOT_YET_RECRUITING

    Dijon, Côte d'Or, 21079, France

    Contact Email: •••••@•••••

    Contact

  • Centre Hospitalier de Montpellier

    RECRUITING

    Montpellier, Hérault, 34090, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Hospitalier de Nîmes

    RECRUITING

    Nîmes, GARD, 30900, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Centre Léon Bérard

    NOT_YET_RECRUITING

    Lyon, Rhône, 69373, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut Bergonié

    NOT_YET_RECRUITING

    Bordeaux, Gironde, 33076, France

    Contact Email: •••••@•••••

    Contact

  • Institut de Cancérologie de l'Ouest

    RECRUITING

    Angers, Maine Et Loire, 49055, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Institut régional du Cancer de Montpellier

    RECRUITING

    Montpellier, Hérault, 34298, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Negative pressure therapy (a special dressing connected to a vacuum to help wounds heal)

What this could lead to

If it works, this could offer a simple way to reduce infections, wound reopening, and slow healing after breast cancer surgery with reconstruction.

What could go wrong

This is a relatively small, early-stage trial. Previous studies had serious limitations, so results may not be conclusive. The therapy is a procedure, not a drug, so benefits may be modest.

Conditions

The condition(s) this trial relates to.

breast neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.