Institut Cancerologie De L'ouest
Clinical trials sponsored by Institut Cancerologie De L'ouest, explained in plain language.
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Personalized chemo dosing may help elderly pancreatic cancer patients maintain independence
Disease control CompletedThis study tested a chemotherapy combination called FOLFIRINOX, with doses adjusted based on patients' genetics, in 72 people aged 70 and older with metastatic pancreatic cancer. The goal was to see if this approach could control the cancer while reducing side effects and helping…
Phase: PHASE2 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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New combo therapy shows promise in delaying prostate cancer relapse
Disease control CompletedThis study looked at 74 men with prostate cancer that had come back in up to 5 pelvic lymph nodes after initial treatment. They received high-dose radiation to those spots plus hormone therapy. The goal was to see if this approach could delay the cancer from growing again. The ma…
Phase: PHASE2 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Disease control
Last updated May 19, 2026 11:48 UTC
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New imaging agent spots hidden breast cancer tumors
Diagnosis CompletedThis study tested a new radioactive tracer called 89Zr-TLX250 that attaches to a protein found on some triple negative breast cancer cells. 12 people with advanced cancer received a PET scan using this new tracer, and doctors compared it to a standard PET scan to see which one fo…
Phase: PHASE2 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Diagnosis
Last updated May 26, 2026 05:09 UTC
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New scan could spot bladder cancer earlier
Diagnosis CompletedThis early study tested a new imaging agent called 89Zr-girentuximab to see if it can help detect non-muscle-invasive bladder cancer using PET/CT scans. Six adults with confirmed bladder cancer took part. The goal was to check safety and how well the scan shows cancer spots.
Phase: EARLY_PHASE1 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Diagnosis
Last updated May 26, 2026 04:36 UTC
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Can a special PET scan outperform MRI for spotting brain tumors?
Diagnosis CompletedThis study tested whether a special type of PET scan (called 18F-DOPA PET-CT) can find brain metastases as well as or better than the standard MRI. Researchers looked at 32 patients with lung cancer, breast cancer, or melanoma who had untreated brain metastases. The goal was to s…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Diagnosis
Last updated May 22, 2026 13:53 UTC
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Breathing support after surgery fails to reduce lung complications
Prevention CompletedThis study tested whether giving patients a breathing mask (noninvasive ventilation) right after surgery could prevent serious lung problems. It included 266 adults at high risk for lung complications, based on a scoring tool called ARISCAT. The results showed that early breathin…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Prevention
Last updated May 20, 2026 11:57 UTC
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Fat grafting before implant may ease pain and improve breast reconstruction
Symptom relief CompletedThis study tested a breast reconstruction method for women who had a mastectomy (breast removal) due to breast cancer. The approach places a breast implant under the skin instead of under the chest muscle, after using fat grafts to prepare the area. The goal was to see if this me…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 26, 2026 05:10 UTC
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Exercise eases fatigue for cancer patients, study shows
Symptom relief CompletedThis study looked at whether a 12-week exercise program could improve fatigue, quality of life, and fear of movement in cancer patients. 37 adults with any cancer type and treatment took part. Researchers measured changes using a standard fatigue and quality-of-life questionnaire…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 26, 2026 05:06 UTC
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Pepper patch may beat pills for Post-Surgery breast cancer pain
Symptom relief CompletedThis study tested whether a capsaicin skin patch (made from chili peppers) works better than oral pregabalin for nerve pain that starts soon after breast cancer surgery. 140 patients were randomly assigned to one of the two treatments. The goal was to see if early treatment with …
Phase: PHASE3 • Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 26, 2026 04:38 UTC
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Meditation audio eases breast biopsy anxiety, study finds
Symptom relief CompletedThis study looked at whether listening to guided meditation during a breast biopsy can help reduce pain and anxiety. 225 people having a breast biopsy took part. They filled out questionnaires about their pain and anxiety before and after the procedure. The goal was to see if thi…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 26, 2026 04:35 UTC
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Virtual reality goggles ease pain for cancer surgery patients
Symptom relief CompletedThis study tested whether using virtual reality (VR) during cancer surgery under local anesthesia can lower pain and anxiety. 42 adults with cancer took part. One group had standard local anesthesia, the other also wore a VR headset showing calming scenes. The goal was to see if …
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 22, 2026 13:54 UTC
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Fat grafting offers natural breast reconstruction alternative
Symptom relief CompletedThis study tested a breast reconstruction method that uses only a patient's own fat (lipomodulin) instead of implants or tissue flaps. It included 118 women who had a mastectomy for breast cancer. The goal was to see how well the technique works, how the breast looks afterward, a…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Symptom relief
Last updated May 15, 2026 11:55 UTC
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Kids' social background linked to chemical exposure and DNA damage
Knowledge-focused CompletedThis study looked at 149 children aged 8 to 12 from different social and economic backgrounds in France. Researchers collected hair samples to measure chemical exposure and DNA damage. The goal was to understand how social inequalities affect children's exposure to pollutants and…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 26, 2026 05:15 UTC
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Quick fix for chemo catheters: which method wins?
Knowledge-focused CompletedThis study looked at two methods to handle a central venous catheter that won't draw blood before chemotherapy. One method uses a dye injection and X-ray, the other uses a simple chest X-ray followed by a saline infusion. The goal was to see which method lets doctors decide faste…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 26, 2026 05:11 UTC
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Cancer centers join forces to track COVID-19's toll on patients and staff
Knowledge-focused CompletedThis study looked at how COVID-19 affected cancer patients and healthcare workers in French cancer centers. Researchers tracked infections, immune responses, and the impact on cancer care. Over 1,100 people took part, including patients on treatment, those in follow-up, and staff…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 26, 2026 05:10 UTC
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Timing is everything: study links surgery delays to worse cancer outcomes
Knowledge-focused CompletedThis study looked at 227 people with colorectal cancer that had spread to the lining of the belly. Researchers wanted to see if waiting longer between chemotherapy and surgery hurt chances of survival. The goal is to find the best timing for treatment to help patients live longer…
Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 26, 2026 04:38 UTC
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Do brain radiotherapy masks mess up MRI scans? small study finds out
Knowledge-focused CompletedThis study checked whether the plastic masks used to hold the head still during brain radiotherapy affect the quality of MRI scans needed for treatment planning. Three healthy volunteers had MRI scans with and without two types of masks. The goal was to see if the masks cause err…
Phase: NA • Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 22, 2026 14:01 UTC
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New study reveals how breast reconstruction technique affects pain and recovery
Knowledge-focused CompletedThis study looked at 27 women with breast cancer who had a mastectomy and immediate breast reconstruction using an implant. The implant was placed either above or below the chest muscle, based on the patient's body and preference. Researchers measured pain, arm function, quality …
Sponsor: Institut Cancerologie de l'Ouest • Aim: Knowledge-focused
Last updated May 22, 2026 13:54 UTC