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Quick fix for chemo catheter blockages tested in new study

NCT ID NCT05100355

Symptom relief Sponsor: Institut Cancerologie de l'Ouest Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two methods to manage blocked central venous catheters (CVCs) in 92 cancer patients before chemotherapy. One method used a chest X-ray followed by a saline injection, while the other used a contrast dye injection. The goal was to see which approach allowed doctors to decide faster whether to proceed with chemo on the same day.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could lead to a faster, safer way to clear blocked catheters, allowing chemotherapy to start on time without unnecessary procedures.
What could go wrong
This is a small, completed study with only 92 participants, so results may not apply to all patients. Both methods are routine, so no major breakthrough is expected.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

92 people

The number who actually took part.

Started

Mar 2022

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Female or male, Age ≥ 18 years at time of study entry. * Undergoing systemic chemotherapy on a CVC. Immunotherapy and targeted therapies are among the systemic therapies that are authorised * Having already received at least one administration of treatment without difficulty. * Coming for a new administration of treatment authorised by the usual biological assessment. * First episode of lack of CVC blood return despite the usual positioning and injection- aspiration manoeuvres * No abnormality on inspection or palpation (turning) of the CVC. * Patient has valid health insurance. * Patient information and signature of informed consent. Exclusion Criteria: * Previous episode of lack of CVC blood return whether explored or not. * Patient currently treated in an interventional therapeutic trial. * Patient with a Picc-line implantable device. * Suspected CVC infection or thrombosis. * Planned chemotherapy with vesicant agent (anthracyclines). * Possible CVC disjunction. * Allergy to X-ray contrast agent or creatinine clearance below 30ml/min prohibiting an iodine injection. * Pregnant, likely to be pregnant or breastfeeding woman. * Persons deprived of their liberty, under a measure of safeguard of justice, under guardianship or placed under the authority of a guardian. * Impossibility of undergoing medical monitoring of the trial for geographical, social or psychological reasons, social or psychological reasons.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Catheter dysfunction

Contacts and locations

Locations

  • Audrey ROLLOT

    Saint-Herblain, 44805, France

  • CH Yves Le Foll

    Saint-Brieuc, 22023, France

  • CHBA Vannes

    Vannes, 56017, France

  • CHD La Roche Sur yon

    La Roche-sur-Yon, 85925, France

  • Centre Eugène Marquis

    Rennes, 35042, France

  • Centre Hospitalier de St Malo

    St-Malo, 35400, France

  • Ch Cholet

    Cholet, 49300, France

  • Institut de Cancérologie de l'Ouest

    Angers, 49055, France

  • Institut du Cancer Sainte Catherine Avignon Provence

    Avignon, 80005, France

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