Insel Gruppe Ag, University Hospital Bern

This study tests whether semaglutide (a GLP-1 drug used for diabetes and weight loss) can help people with obesity and fatty liver disease reduce or stop drinking alcohol. 64 participants will receive either semaglutide injections plus lifestyle counseling, or counseling alone. T…

This study looks at whether taking a mix of probiotics (good bacteria) can change the gut microbiome of children and teens aged 5-18 with inflammatory bowel disease (IBD). About 40 participants will be randomly assigned to take probiotics or a placebo, then switch after a period.…

This study tests two approaches to prevent kidney stones from coming back in people who have had them before. One approach uses a daily pill called empagliflozin (a diabetes drug) and the other gives personalized diet advice based on urine tests. The trial will involve 400 adults…

This study tests whether people with giant cell arteritis (GCA) can safely take steroids for only 8 weeks instead of the usual 26 weeks when also using the drug tocilizumab. About 178 participants will be randomly assigned to one of two treatment lengths. The goal is to see if th…

This study tests whether a single injection of fremanezumab, a drug used to prevent migraines, can stop acute mountain sickness (AMS) in healthy adults. Thirty volunteers will receive either the drug or a placebo one week before climbing to a high-altitude hut. Researchers will t…

This trial tests whether a 12-week home rehabilitation program using the Akina app is as effective as standard outpatient physiotherapy for older adults (ages 55-80) recovering from hip surgery. Sixty-six participants will either use the digital program at home or receive routine…

This study tests whether adding the drug dexmedetomidine during carotid artery surgery helps keep blood pressure more stable. About 44 adults having this surgery will be randomly assigned to receive either standard anesthesia alone or standard anesthesia plus dexmedetomidine. The…

This study looks at whether turning on a cochlear implant affects a person's sense of direction and balance. Seven hundred adult cochlear implant users will take online surveys and perform balance tests under different implant settings. The goal is to see if the implant's sound c…

This study aims to find out what children, their parents, and doctors think are the most important research topics in pediatric anesthesia and surgery care. About 1,040 participants in Switzerland will share their views through online surveys. The results will help guide future s…

This study looks at how sleep apnea test results vary from night to night. Researchers will track 192 people with suspected or diagnosed sleep apnea over multiple nights at home. The goal is to find which measurements are most stable and reliable for diagnosis, potentially improv…

This study aims to understand how synthetic nicotine and nicotine-like chemicals affect the body compared to regular tobacco nicotine. Researchers will measure nicotine levels in the blood of 24 adult vapers after they use different products. The goal is to learn more about their…

This study tests whether the Stockholm3 blood test can accurately detect when low-risk prostate cancer becomes more aggressive in men who are closely monitored instead of treated immediately. Researchers will enroll 350 men on active surveillance to see if the test can reduce the…