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Weight-Loss drug may curb alcohol cravings in fatty liver patients

NCT ID NCT06546384

First seen Mar 12, 2026 · Last updated Jun 23, 2026 · Updated 12 times

Summary

This study tests whether semaglutide (a GLP-1 drug used for diabetes and weight loss) can help people with obesity and fatty liver disease reduce or stop drinking alcohol. 64 participants will receive either semaglutide injections plus lifestyle counseling, or counseling alone. The main goal is to see if more people in the drug group achieve total alcohol abstinence after 16 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University Hospital Bern

    Bern, 3010, Switzerland

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

semaglutide

What this could lead to

If it works, this could point toward a new way to help people with obesity and fatty liver cut down on alcohol.

What could go wrong

This is a small, early-stage trial with only 64 people. It may not show a clear benefit, and semaglutide can cause nausea and other side effects.

Conditions

The condition(s) this trial relates to.

alcohol abuse fatty liver disease Obesity obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.