Imperial College London

This study is testing a new treatment approach for people with advanced, fast-growing neuroendocrine tumors who haven't had chemotherapy for their spread-out disease. It combines a short course of chemotherapy and an immunotherapy drug, followed by long-term maintenance therapy w…

This study is testing whether a drug called XBD173 can improve blood flow in the brains of people with Alzheimer's disease. Participants with mild to moderate Alzheimer's will take either the drug or a placebo pill for 28 days while researchers measure brain blood flow and other …

This early-stage study is testing the safety of a drug called dostarlimab for people with HIV and a rare, treatment-resistant cancer called Kaposi sarcoma. Dostarlimab is an immunotherapy designed to help the body's own immune system fight cancer cells. The study will enroll up t…

This study aimed to test the safety of a new procedure for Type 1 diabetes. Researchers planned to transplant insulin-producing cells into the front part of the eye in six participants who already had vision problems. The main goal was to see if this unusual location was safe and…

This study is testing whether it's practical to run a larger trial using digital tools to help older adults adopt healthier habits. It involves 30 people aged 65+ in London who are starting to feel less robust. Participants will use smartwatches and apps for 3-6 months, or receiv…

This study is testing whether sending mailed reminders and providing a patient guide can help more people with liver cirrhosis or chronic hepatitis B attend their regular liver cancer screening appointments. Researchers want to see if this support helps catch cancer at an earlier…

This study aimed to see if a drug called Capivasertib could help prevent breast cancer from coming back. It focused on women with a specific type of breast cancer who had finished their main treatment but had tiny traces of cancer DNA in their blood, which is an early warning sig…

This study aims to gather basic information to help design future research for a serious lung condition called pulmonary arterial hypertension (PAH). Researchers are using PET scans to see how much of an experimental compound, XBD173, reaches and binds to a specific protein in th…