Scientists test how experimental drug hooks into lung protein
NCT ID NCT07362290
First seen Jan 31, 2026 · Last updated Jun 23, 2026 · Updated 19 times
Summary
This study looks at how an experimental drug called XBD173 attaches to a protein (TSPO) in the lungs of 16 healthy volunteers. Using PET scans, researchers will measure how much of the drug is needed to block the protein and whether food affects drug levels. The goal is to gather basic information for future research on lung diseases.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
-
NIHR Imperial CRF
London, W12 0HS, United Kingdom
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
XBD173
What this could lead to
If successful, this could help design future studies on TSPO's role in lung diseases like pulmonary arterial hypertension.
What could go wrong
This is a very early, small study in healthy volunteers, not patients. It only measures drug binding, not any treatment effect, so it may not lead to any therapy.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.