Icahn School Of Medicine At Mount Sinai

This study tests a combination of three drugs (iberdomide, elotuzumab, and dexamethasone) in people whose multiple myeloma has come back or stopped responding to treatment. The goal is to find a safe dose that can shrink or control the cancer. Up to 37 adults will take part, star…

This early-phase study tested a concentrated herbal formula (E-B-FAHF-2) in 7 adults with mild-to-moderate Crohn's disease. The main goal was to see if the treatment is safe and tolerable. Researchers also looked for signs that the formula might help control inflammation and main…

This study compares a lower dose of radiation to the standard dose for people with advanced HPV-positive throat cancer. The goal is to see if the reduced dose can control the cancer just as well while causing fewer side effects. The trial includes 23 participants with stage 3 or …

This study tests a program called SaMBA-WTC to help World Trade Center responders with asthma better manage their condition. About 56 adults with uncontrolled asthma will be randomly assigned to the program or a control group. The goal is to see if the program improves asthma con…

This study tests whether specialized in-home palliative care can improve symptom management for people with advanced dementia and reduce stress for their family caregivers. About 153 patient-caregiver pairs in New York City will receive either the in-home care or standard support…

This study tests a new way to deliver palliative care at home for 60 people with advanced heart failure or certain cancers. The care team grows as symptoms worsen, starting with a community health worker and adding a social worker, nurse, or doctor as needed. The goal is to see i…

This study explores whether using a virtual reality headset for guided meditation at the start of voice therapy sessions can help people with voice disorders learn and retain treatment better. About 60 participants will use the TRIPP app on a Meta Quest 2 headset to calm their mi…

This study tests whether a device called MIRA, which provides calming audio and visual experiences, is safe and helpful for patients and staff in a neuroscience intensive care unit (NSICU). The goal is to see if it can improve physical, mental, and cognitive health after an ICU s…

This study tests a program called NeuroResource Facilitation for people with brain injury who are about to leave prison. The goal is to see if it helps them stay out of trouble and avoid being arrested again. Over 1,000 adults in Pennsylvania are taking part.

This study looks at whether a nasal spray of oxytocin, sometimes called the 'love hormone,' can improve trust and cooperation in people with borderline personality disorder (BPD). Researchers will compare how BPD patients and healthy adults play a trust game, both with and withou…

This study looked at whether telling women about calcium buildup in their breast arteries (found during a mammogram) could encourage them to take steps for better heart health. Over 5,000 women took part, and a smaller group received their calcium results along with their usual m…

This study looks at over 1,000 adults with asthma to better understand different types of the disease. Researchers will use medical records and genetic information to see how asthma responds to various treatments. No new treatments are tested; the goal is to gather knowledge that…

This study looks at whether a single dose of methylphenidate (a drug used for ADHD) can help people with cocaine addiction weaken their drug-related memories. Researchers will use brain scans and skin response measurements to see how the drug affects memory retrieval and cravings…