Icahn School Of Medicine At Mount Sinai

This study tests a device called the Numen SILK coil, which is placed into the middle meningeal artery to block blood flow and help resolve chronic subdural hematoma—a slow brain bleed common in older adults. Researchers will enroll 100 people to see if this minimally invasive pr…

This trial tests whether removing a brain bleed with a minimally invasive scope within hours of symptoms improves recovery. 300 adults with a specific type of brain bleed will be randomly assigned to either get the surgery plus standard care, or standard care alone. The study wil…

This study tests whether using detachable coils to block blood vessels in the brain can safely treat chronic subdural hematoma—a buildup of blood on the brain's surface common in older adults. About 150 participants will receive the coil procedure, with or without standard surgic…

This study tests whether group care—where patients meet together with health workers for education and check-ups—can improve control of high blood pressure and diabetes in Nepal. Over 1,100 adults from 37 health facilities will be assigned to standard care, low-intensity group ca…

This study compares two ways to manage diabetes after hospital discharge: using a continuous glucose monitor (CGM) versus standard fingerstick checks. About 64 adults with type 2 or steroid-induced diabetes who need insulin after leaving the hospital will wear a sensor for 28 day…

This study tests whether high-intensity focused ultrasound (HIFU) can safely shrink prostate tissue in men aged 45–80 with bladder outlet obstruction caused by an enlarged prostate (BPH). About 17 participants will receive the procedure and be followed for 6–12 months to see if u…

This study tests whether a combination of three drugs—valacyclovir, celecoxib, and Paxlovid—can reduce Long COVID symptoms in adults compared to a placebo. Researchers will enroll 150 people aged 18-65 with a Long COVID diagnosis. The goal is to see if this approach improves over…

This study tests whether a drug called sotagliflozin can prevent heart, muscle, and fat damage caused by a common type of chemotherapy (anthracycline) in people with newly diagnosed lymphoma. About 60 adults who are scheduled to receive high-dose anthracycline will take either th…

This study tests whether a 5-week heart rate variability biofeedback program (a guided breathing technique) can reduce symptoms like belly pain and bloating in 23 adults with active ulcerative colitis but no active gut inflammation. Participants will be followed for 17 weeks. The…

This study tests whether a combination of real-time brain training (using a wearable brain scanner called fNIRS) and personalized text messages can help women with bulimia nervosa improve self-control and reduce binge eating. Forty women aged 18-55 will receive either real or sha…

This study tests a flexible palliative care program for people with advanced heart failure or certain cancers. The program adds more team members—like a social worker or nurse—as symptoms get worse. The goal is to improve quality of life and match care to each person's changing n…

This study tests a group therapy program called HOPE-LC~Español for Spanish-speaking adults with Long COVID. The program teaches coping skills and resilience. Researchers will enroll 25 people in Queens to see if the program is helpful and practical.

This early study tests whether a low-level magnetic therapy device, used at home, is safe and practical for people with cognitive issues from brain injury, Long COVID, or Alzheimer's. About 30 adults will use the device regularly and complete computer-based thinking tests. The go…

This study tests a virtual education program called LIFT-ECHO, where non-specialist doctors learn from experts how to better manage chronic intestinal failure. Researchers will enroll 150 patients and their doctors, tracking quality of life and disease activity over 12 months. Th…

This small study will test whether a stomach ultrasound can work in people who have already had bariatric surgery. Ten adults scheduled for another surgery will have their stomachs scanned before and after the procedure. The goal is to see if ultrasound can measure stomach size a…