Glaxosmithkline

This study tests a new combination vaccine that protects against measles, mumps, rubella, and chickenpox (MMRV) in healthy children aged 15 months to 6 years. The vaccine is given as a second dose to children who already received a first dose of similar vaccines. Researchers will…

This early-stage study tests a new pneumococcal vaccine booster (Pn-MAPS30plus) in 45 healthy toddlers aged 12-15 months who already received their routine pneumonia shots. The goal is to check for side effects like tenderness, fever, or sleepiness compared to a standard vaccine.…

This study tests a single dose of a combined diphtheria, tetanus, and pertussis (whooping cough) vaccine in healthy pregnant women in Japan. The goal is to see how well the vaccine boosts immunity in mothers and passes protection to their newborns. About 95 women between 27 and 3…

This study tests a new drug, GSK5733584, against standard chemotherapy for people whose endometrial cancer has come back or spread. About 600 adults will take part to see if the new drug shrinks tumors better and helps people live longer without the cancer growing. The goal is to…

This study tests a new drug, GSK3862995B, in 400 adults with bronchiectasis, a chronic lung disease. The goal is to see if the drug can reduce the number of serious lung infections (exacerbations) compared to a placebo. Participants will receive one of two doses of the drug or a …

This study tests a new medicine called Risvutatug Rezetecan (Ris-Rez) in adolescents and adults with advanced bone or soft tissue sarcomas that have returned or spread and cannot be removed by surgery. The goal is to see if the drug can shrink tumors or slow cancer growth, and to…

This study tests a new drug, GSK5733584, against standard chemotherapy in 450 people with ovarian cancer that has stopped responding to platinum-based treatments. The main goals are to see if the new drug helps people live longer without their cancer growing and to check its safe…

This study tests a drug called momelotinib in 192 adults with VEXAS syndrome, a rare genetic condition causing severe inflammation. Participants will receive either the drug or a placebo to see if it can control the disease. The goal is to measure how many people achieve a comple…

This study tests a new drug called velzatinib against the standard treatment imatinib for people with a type of stomach or intestinal cancer (GIST) that has spread or cannot be removed by surgery. About 800 adults who have not had prior treatment for advanced GIST will take part.…

This study tests a new drug, belantamab mafodotin, added to standard chemotherapy for adults newly diagnosed with AL amyloidosis, a rare disease where abnormal proteins build up in organs. About 60 participants will receive different doses to find the best balance of effectivenes…

This study tests a new oral drug, GSK3772701, in 70 adults with uncomplicated malaria caused by P. falciparum. The goal is to find safe and effective doses and treatment lengths. Participants will take the drug for a short time and be monitored for side effects and how well the d…

This study tests a new medicine called depemokimab for people with Type 2 asthma who are at risk of asthma attacks. The goal is to see if adding this drug to standard care can reduce attacks, help patients achieve remission (no attacks and no need for steroid pills), and slow lun…

This early-stage study tests a new pneumococcal vaccine (Pn-MAPS30plus) in 60 healthy infants to see if it is safe and what side effects it causes. Babies will receive three doses starting around 2 months old, followed by a booster at 12-15 months. The study compares the new vacc…

This study tests a new drug called camlipixant in 420 adults with moderate-to-severe irritable bowel syndrome (IBS) that causes diarrhea or mixed bowel habits. Participants will receive either the drug or a placebo for 26 weeks to see if it reduces abdominal pain and improves sto…

This early-stage study will test a single dose of the experimental antibiotic gepotidacin in 20 hospitalized children aged 2 to 12 who are already receiving standard antibiotics for a bacterial infection or as a preventive measure. The main goal is to see how the drug moves throu…

This early-stage study tests a new drug called GSK4771261 in 30 healthy adults of Chinese, Japanese, and White/European ancestry. The main goal is to check if the drug is safe and how the body processes it after a single injection. This study does not treat any disease but gather…

This study follows African children who received a Shigella vaccine in earlier studies to see how long their immune protection lasts. No new vaccines are given—only blood samples are taken at 1, 2, and 3 years after the last shot. The goal is to understand the vaccine's long-term…