Eye & Ent Hospital Of Fudan University

This study is for people with a rare sinus cancer called sinonasal adenoid cystic carcinoma. The treatment delivers high-dose chemotherapy directly to the tumor through a small tube in an artery, aiming to shrink it as much as possible. After three sessions, doctors check if the …

This study follows 300 deaf patients of all ages who receive cochlear implants, tracking their hearing, speech, and quality of life over time. Researchers aim to see how different age groups and treatment types respond, to personalize rehabilitation. Participants must have severe…

This phase 2 trial is testing whether giving immunotherapy (Toripalimab) and chemotherapy (Temozolomide) before surgery can improve outcomes for people with a rare type of melanoma in the nasal cavity. The study will enroll 25 participants with resectable tumors. The main goal is…

This phase 2 trial is testing whether giving the immunotherapy drug tislelizumab along with chemotherapy before surgery can shrink advanced squamous cell carcinoma of the ear canal. The goal is to make surgery easier and safer, especially to protect important nerves near the ear.…

This study tests whether adding the drug finotonlimab to standard chemotherapy before surgery can improve outcomes for people with advanced hypopharyngeal cancer (a type of throat cancer). About 116 adults who have not had prior treatment will be randomly assigned to receive eith…

This study is for people with hypopharyngeal cancer that has spread to neck lymph nodes. It compares a new treatment plan to standard care to see if it can delay cancer growth or improve survival. About 111 adults aged 18-75 with good overall health can join.

This study tests a tiny retinal implant (AuTNA I) placed under the retina to help people with retinitis pigmentosa, a genetic condition that causes vision loss. Seven participants aged 18-70 will be monitored for one year to check safety and whether the implant improves light sen…

This study compares two treatments for a type of crossed eye (small-angle esotropia) that started recently. One group will do special eye exercises, and the other will wear prism glasses. The goal is to see which approach better straightens the eyes and improves 3D vision. About …

This study tests a combination of two drugs (Becotatug vedotin and epirubicin) given before surgery to people with a rare type of sinus cancer that has come back and cannot be removed. The goal is to shrink the tumor enough so that surgery becomes possible or to better control th…

This early study tests a new eye drop called JN002 in 30 adults with dry eye disease. Participants will use the drops three times a day for 28 days. The goal is to see if the drops are safe and if they improve symptoms and eye surface health compared to a placebo.

This study tests whether adding acupuncture to standard steroid treatment helps people recover hearing after sudden sensorineural hearing loss. 256 adults will receive either real or sham acupuncture three times a week for four weeks, along with oral steroids. The main goal is to…

This study will compare how well people with congenital hearing loss can hear and speak after receiving either gene therapy or a cochlear implant. Researchers will also include healthy participants for comparison. The goal is to understand the differences in hearing outcomes and …

This study looks at 90 cataract patients who also have an epiretinal membrane (a thin layer on the retina). Researchers want to see if a special "functional" lens implant helps them see better without glasses compared to a standard lens. Participants will have their vision checke…

This study looks at 1,000 people with throat cancer (laryngeal or hypopharyngeal) to compare different treatments like surgery, radiation, and chemotherapy. The goal is to see which treatments lead to the best survival rates and help preserve the voice. By analyzing outcomes for …