Eye & Ent Hospital Of Fudan University

This study tests whether giving chemotherapy plus the drug tislelizumab before surgery can shrink advanced squamous cell carcinoma of the ear canal and help preserve important nerves like the facial nerve. About 50 adults with previously untreated, locally advanced cancer will re…

This study is for people with hypopharyngeal cancer that has spread to neck lymph nodes. It compares a new treatment plan to standard care to see if it can delay cancer growth or improve survival. About 111 adults aged 18-75 with good overall health can join.

This study follows 300 deaf patients of all ages who are getting a cochlear implant. Researchers will test hearing, speech, and quality of life before and after the implant to see how well it works and how to improve care. The goal is to personalize hearing and speech rehabilitat…

This study tests a tiny retinal implant (AuTNA I) placed under the retina to help people with retinitis pigmentosa, a genetic condition that causes vision loss. Seven participants aged 18-70 will be monitored for one year to check safety and whether the implant improves light sen…

This study is for people with a rare and aggressive type of melanoma that starts in the nasal and sinus passages. Researchers want to see if giving immunotherapy and chemotherapy before surgery can help prevent the cancer from spreading. The study will enroll 25 adults whose tumo…

This study tests a new way to treat a rare sinus cancer called sinonasal adenoid cystic carcinoma. Doctors deliver a strong chemotherapy drug directly to the tumor through a small tube, aiming to shrink it as much as possible. After three treatments, scans will show if the tumor …

This study compares two treatments for a type of crossed eye (small-angle esotropia) that started recently. One group will do special eye exercises, and the other will wear prism glasses. The goal is to see which approach better straightens the eyes and improves 3D vision. About …

This study tests whether adding the drug finotonlimab to chemotherapy before surgery can help people with advanced hypopharyngeal cancer live longer without the cancer coming back. About 116 adults aged 18 to 75 who have not had prior treatment will take part. The approach aims t…

This study tests a combination of two drugs (Becotatug vedotin and epirubicin) given before surgery to people with a rare type of sinus cancer that has come back and cannot be removed. The goal is to shrink the tumor enough so that surgery becomes possible or to better control th…

This early-stage study tests a new eye drop called JN002 in 30 adults with dry eye disease. Participants will use the drops three times a day for 28 days. The goal is to see if the drops are safe and can improve eye comfort and tear film health compared to a placebo.

This study tests whether adding acupuncture to standard steroid pills helps people with sudden hearing loss recover more hearing. About 256 adults will receive either real or sham acupuncture three times a week for four weeks, plus a two-week course of prednisone. The main goal i…

This study looks at whether a special type of artificial lens (functional IOL) helps people who have both cataracts and a thin scar on the retina (epiretinal membrane) see better than a standard lens. About 90 adults over 40 who need cataract surgery and have this retinal conditi…

This study looks at 1,000 people with throat cancer (laryngeal or hypopharyngeal) to compare how well different treatments work for each cancer stage. Treatments include surgery, radiation, chemotherapy, or a mix, based on standard guidelines. The goal is to find which approach g…

This study compares how well people with a genetic form of deafness (DFNB9) can hear and understand speech after receiving either a cochlear implant or gene therapy. Researchers will measure hearing ability, speech understanding, and thinking skills in 180 participants, including…