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Gene therapy vs. cochlear implants: which restores hearing better?

NCT ID NCT06237790

First seen Sep 30, 2025 · Last updated Jun 23, 2026 · Updated 34 times

Summary

This study will compare how well people with congenital hearing loss can hear and speak after receiving either gene therapy or a cochlear implant. Researchers will also include healthy participants for comparison. The goal is to understand the differences in hearing outcomes and improve rehabilitation plans for gene therapy patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Eye & ENT Hospital of Fudan University

    RECRUITING

    Shanghai, Shanghai Municipality, 200031, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Peking Union Medical College Hospital

    NOT_YET_RECRUITING

    Beijing, Beijing Municipality, 100730, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Nanchang University

    NOT_YET_RECRUITING

    Nanchang, Jiangxi, 330006, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Affiliated Hospital of Zhengzhou University

    NOT_YET_RECRUITING

    Zhengzhou, Henan, 450052, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Second Xiangya Hospital of Central South University

    NOT_YET_RECRUITING

    Changsha, Hunan, 410011, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital, Sichuan University

    NOT_YET_RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

gene therapy

What this could lead to

If successful, this study could help doctors create better rehabilitation plans for patients receiving gene therapy for deafness.

What could go wrong

This is an observational study, not a treatment trial. It compares existing outcomes, so it won't directly test if gene therapy works better than cochlear implants.

Conditions

The condition(s) this trial relates to.

hearing loss disorder hereditary disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.