European Organisation For Research And Treatment Of Cancer - Eortc

This study tests whether the drug tebentafusp can prevent uveal melanoma (a rare eye cancer) from returning in patients at high risk of recurrence after standard treatment. About 290 adults with a specific genetic type (HLA-A*02:01) will be randomly assigned to receive tebentafus…

This study tests whether adding precise, high-dose radiation (SABR) to the standard immunotherapy drug pembrolizumab can help people with head and neck cancer that has spread to up to 5 places in the body. About 200 adults with this type of cancer will be randomly assigned to rec…

This study tests whether a daily pill called vorasidenib can delay tumor growth in people with a specific type of slow-growing brain tumor (IDH-mutant astrocytoma) after they finish standard radiation and chemotherapy. About 468 adults will be randomly assigned to receive either …

This study tests a new treatment for people with recurrent meningioma, a type of brain tumor that has come back after surgery or radiation. The treatment uses a radioactive drug called 177Lu-DOTATATE, which targets tumor cells and delivers radiation directly to them. About 136 ad…

This study tests whether adding a second round of radiation to the chemotherapy drug lomustine helps people with glioblastoma that has come back after initial treatment. About 411 participants will be randomly assigned to receive lomustine alone or lomustine plus targeted radiati…

This study tests a drug called elacestrant against standard hormone therapy in 220 people with ER+/HER2- breast cancer who show signs of cancer DNA in their blood (ctDNA) but no distant spread. The goal is to see if elacestrant can delay or prevent the cancer from returning elsew…

This study tests whether men with metastatic hormone-sensitive prostate cancer can safely take breaks from hormone therapy after an initial treatment period. About 1,600 participants who have already responded well to therapy will be randomly assigned to either continue treatment…

This study tests whether giving chemotherapy before surgery helps people with high-risk retroperitoneal sarcoma (a rare cancer in the abdomen) live longer without the cancer coming back. About 250 adults with specific sarcoma types will be randomly assigned to receive chemo then …

This study tests whether continuing the immunotherapy drug cemiplimab for up to a year can help people with stage IV non-small cell lung cancer that has spread to only a few spots (oligometastatic). After initial treatment with cemiplimab plus chemotherapy and targeted radiation …

This study watches 1650 people with different types of brain tumors to see if the new 2021 classification system helps doctors choose better treatments. Researchers will track how long patients live and how well their tumors respond to therapy. The goal is to create clearer treat…

This study collects tumor samples, images, and health information from nearly 5,000 cancer patients to build a high-quality research platform. The goal is to better understand tumor biology and help match patients to the most suitable clinical trials. Participants must be at leas…