Could chemo before surgery beat sarcoma? new trial aims to find out

NCT ID NCT04031677

Disease control Sponsor: European Organisation for Research and Treatment of Cancer - EORTC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Sep 11, 2026 · Updated 2 times

Summary

This study is for people with a rare, high-risk cancer called retroperitoneal sarcoma. It compares two approaches: getting chemotherapy before surgery versus surgery alone. The goal is to see if the chemo-first approach helps prevent the cancer from coming back. About 250 participants will be enrolled across multiple centers.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 3

Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.

Participants

About 250 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2021

Expected to finish

Apr 2028

An estimate. End dates often move.

Lead sponsor

A research network

The lead sponsor is a research network or cooperative group.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

1. STRASS 2 Inclusion Criteria: * Histologically proven primary high risk leiomyosarcoma (LMS) or Liposarcoma (LPS) of retroperitoneal space or infra-peritoneal spaces of pelvis. * LMS: * Any grade LMS can be included * Minimum size of LMS tumor should be 5 cm * LPS: * Diagnosis should be confirmed based on MDM2 (Mouse double minute 2 homolog) and CDK4 (Cyclin-dependent kinase 4) expression on IHC (immunohistochemistry), while proof of MDM2 amplification is highly recommended. * All grade 3 DDLPS can be included. * DDLPS with confirmed grade 2 on biopsy can be included when: * The grade 2 DDLPS has an FNCLCC score=5 (Fédération Nationale des Centres de Lutte Contre Le Cancer), and clear necrosis on imaging (whether or not present on the biopsy). * The tumors carry a high risk gene profile as determined by the Complexity INdex in SARComas (CINSARC-high) * Unifocal tumour * Resectable tumour: resectability is based on pre-operative imaging (CT-abdomen, potentially also with MRI) and has to be defined by the local treating sarcoma team. A patient is not considered resectable when the expectation is that only an R2 resection is feasible. * Criteria for non-resectability are: * Involvement of the superior mesenteric artery, aorta, coeliac trunk and/or portal vein * Involvement of bone * Growth into the spinal canal * Progression of retro-hepatic inferior vena cava leiomyosarcoma towards the right atrium * Infiltration of multiple major organs like liver, pancreas and or major vessels * Patient must have radiologically measurable disease (RECIST 1.1), as confirmed by imaging. CT thorax abdomen pelvis with IV contrast is the preferred imaging modality. In case of any contra-indications (medical or regulatory), it is allowed to perform a non-contrast CT thorax + MRI abdomen \& pelvis * Collection of tumour tissue for central pathology review is mandatory. * For patients with LMS: if there is not enough tissue for assessing the grading, this is acceptable. * If tumour tissue is not available for the central pathology review, patient will not be eligible. * If the biopsy was not done or the FFPE of the biopsy not available but at least 10 unstained slides or one pathological block are available for the central review, that will be considered as acceptable. * For the biopsy if fine needle aspiration (FNA) is performed instead of core needle biopsy (CNB) recommended by the standard guidelines, please contact the EORTC medical monitors for further evaluation. * Collection of tumour tissue and blood samples for translational research is mandatory. * In case there is not enough tissue for TR, a new biopsy is not required and if the patient fulfils all other eligibility criteria, he/she will be eligible. * If the blood samples are not collected, patient will not be eligible. * If the patient refuses the collection of biomaterial for TR, patient will not be eligible even if he/she fulfils all other eligibility criteria * ≥ 18 years old (no upper age limit) * WHO performance status ≤ 2 * Adequate haematological and organ function * American Society of Anaesthesiologist (ASA) score \< 3 * Women of childbearing potential (WOCBP) must have a negative serum pregnancy test within 3 days prior to randomization. Note: a woman is considered of childbearing potential, i.e., fertile, if she is following menarche. She remains of childbearing potential until she becomes post-menopausal or permanently sterile.Permanent sterilisation methods include hysterectomy, bilateral salpingectomy and bilateral oophorectomy. A postmenopausal state is defined as no menses for 12 months without an alternative medical cause. A high follicle stimulating hormone (FSH) level in the postmenopausal range may be used to confirm a post-menopausal state in women not using hormonal contraception or hormonal replacement therapy. However, in the absence of 12 consecutive months without menses, a single FSH measurement is insufficient. * WOCBP in both arms should use highly effective birth control measures, during the study treatment period and for at least 6 months after the last dose of chemotherapy or date of surgery (except for women receiving chemotherapy with ifosfamide who should continue contraception until 1 year after last day of treatment). A highly effective method of birth control is defined as a method which results in a low failure rate (i.e., less than 1% per year) when used consistently and correctly. * For men in the experimental arm: agreement to remain abstinent (refrain from heterosexual intercourse) or use contraceptive measures, and agreement to refrain from donating sperm. * Female subjects who are breast feeding should discontinue nursing prior to the first day of study treatment and until 6months after the last study treatment. * Before patient randomization, written informed consent must be given according to ICH/GCP, and national/local regulations. Exclusion criteria: * Sarcoma originating from bone structure, abdominal or gynecological viscera * Extension through the sciatic notch or across the diaphragm * Metastatic disease * Any previous surgery (excluding diagnostic biopsy), radiotherapy or systemic therapy for the present tumour * Hypersensitivity to doxorubicin, ifosfamide, dacarbazine or to any of their metabolites or to any of their excipients * Congestive heart failure * Angina pectoris * Myocardial infarction within 1 year before randomization * Uncontrolled arterial hypertension defined as blood pressure ≥ 150/100 mm Hg despite optimal medical therapy. Note: in case of high blood pressure: 1) initiation or adjustment of antihypertensive medication(s) is permitted prior to study entry; 2) blood pressure must be re-assessed on two occasions that are separated by a minimum of 1 hour. The mean SBP / DBP values from each blood pressure assessment must be ≤ 150/90mmHg in order for a patient to be eligible for the study. * Uncontrolled cardiac arrhythmia * Previous treatment with maximum cumulative doses (450mg/m² Doxorubicin or equivalent 900mg/m² Epirubicin) of doxorubicin, daunorubicin, epirubicin, idarubicin, and/or other anthracyclines and anthracenediones * Active and uncontrolled infections * Vaccination with live vaccines within 30 days prior to study entry * Inflammation of the urinary bladder (interstitial cystitis) and/or obstructions of the urine flow. * Other invasive malignancy within 5 years, with the exception of adequately treated non-melanoma skin cancer, localized cervical cancer, localized and Gleason ≤ 6prostate cancer. * Uncontrolled severe illness, infection, medical condition (including uncontrolled diabetes), other than the primary LPS or LMS of the retroperitoneum. * Female patients who are pregnant or breastfeeding or female and male patients of reproductive potential who are not willing to employ effective birth control method. * Any psychological, familial, sociological or geographical condition potentially hampering compliance with the study protocol and follow-up schedule; those conditions should be discussed with the patient before randomization in the trial * Known contraindication to imaging tracer and to MRI 2. Selection criteria for STREXIT 2 * Patients with histologically proven primary resectable localized high-risk DDLPS or LMS of retroperitoneal space or infra-peritoneal spaces of pelvis (as described in the inclusion criteria of STRASS 2) and amenable to receive chemotherapy but for whom the list of eligibility criteria for the study is too restrictive (tumour grading not available, inadequate organ function, concomitant diseases) * Patients who meet all eligibility criteria of STRASS 2 but do not consent to randomization or are not enrolled for any other reason. * Patients enrolled in a Registry collecting data on primary RPS patients in the centres participating in STRASS 2 (e.g., RESAR) and who satisfy the above criteria. 3. Selection criteria for preferences for neoadjuvant chemotherapy in STRASS 2 substudy All patients recruited to STRASS 2 in participating centres (Australia +/- international sites) that are able to read, comprehend and write in English at a sufficient level to complete study materials.

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Conditions

The condition(s) this trial relates to.

dedifferentiated liposarcoma leiomyosarcoma liposarcoma retroperitoneal leiomyosarcoma retroperitoneal sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Leiomyosarcoma Liposarcoma Retroperitoneal sarcoma

How to take part

Only the study team decides who joins. These are the ways to reach them.

The places running it

155 sites in 14 countries. The list below names each one and where it is.
The official record

ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

Open the record ↗
A doctor treating you

A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

Aarhus University Hospitals - Aarhus University Hospital-Skejby
RECRUITING

Aarhus, 8250, Denmark
Aichi Cancer Center
RECRUITING

Chikusa-ku, Nagoya, 464-8681, Japan
Allegheny General Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15212, United States
Allegheny Valley Hospital
RECRUITING

Natrona Heights, Pennsylvania, 15065, United States
BCCA - Vancouver Cancer Centre
RECRUITING

Vancouver, British Columbia, V5Z 4E6, Canada
Bank Of Cyprus Oncology Centre
WITHDRAWN

Stróvolos, 2006, Cyprus
Cancer Institute Hospital of JFCR
RECRUITING

Koto-ku, Tokyo, 135-8550, Japan
Carilion Roanoke Memorial Hospital
RECRUITING

Roanoke, Virginia, 24014, United States
Carolinas Medical Center/Levine Cancer Institute
RECRUITING

Charlotte, North Carolina, 28203, United States
Centre Leon Berard
RECRUITING

Lyon, 69008, France
Centro Di Riferimento Oncologico
WITHDRAWN

Aviano, 33081, Italy
Chris O'Brian Life House - Chris O'Brien Lifehouse
RECRUITING

Camperdown, 2050, Australia
City of Hope Comprehensive Cancer Center
RECRUITING

Duarte, California, 91010, United States
Clatterbridge cancer center
RECRUITING

Metropolitan Borough of Wirral, CH63 4JY, United Kingdom
Cooper Hospital University Medical Center
RECRUITING

Camden, New Jersey, 08103, United States
Dana-Farber/Harvard Cancer Center
RECRUITING

Boston, Massachusetts, 02215, United States
Dartmouth Hitchcock Med Ctr/Dartmouth Cancer Ctr
WITHDRAWN

Lebanon, New Hampshire, 03756, United States
Drexel Town Square Health Center
RECRUITING

Oak Creek, Wisconsin, 53154, United States
Duke University Medical Center
RECRUITING

Durham, North Carolina, 27710, United States
Emory University Hospital Midtown
RECRUITING

Atlanta, Georgia, 30308, United States
FHCC South Lake Union
WITHDRAWN

Seattle, Washington, 98109, United States
Forbes Hospital
RECRUITING

Monroeville, Pennsylvania, 15146, United States
Fox Chase Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19111, United States
Fred Hutchinson Cancer Center
RECRUITING

Seattle, Washington, 98109, United States
Froedtert Menomonee Falls Hospital
RECRUITING

Menomonee Falls, Wisconsin, 53051, United States
Froedtert West Bend Hospital/Kraemer Cancer Center
RECRUITING

West Bend, Wisconsin, 53095, United States
Froedtert and MCW Moorland Reserve Health Center
RECRUITING

New Berlin, Wisconsin, 53151, United States
HMH-Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601, United States
Herlev Hospital - University Copenhagen
RECRUITING

Herlev, Copenhagen, 2730, Denmark
Hopital Maisonneuve Rosemont
RECRUITING

Montreal, Quebec, H1T 2M4, Canada
Hopitaux Universitaires de Strasbourg - Hautepierre
WITHDRAWN

Strasbourg, 67098, France
Hospital De La Santa Creu I Sant Pau
RECRUITING

Barcelona, 08041, Spain
Hospital General Universitario Gregorio Maranon
RECRUITING

Madrid, 28007, Spain
Hospital Universitario Fundacion Jimenez Diaz
NOT_YET_RECRUITING

Madrid, 28040, Spain
Hospital Universitario San Carlos
RECRUITING

Madrid, 28040, Spain
Huntsman Cancer Institute/University of Utah
RECRUITING

Salt Lake City, Utah, 84132, United States
IRCCS - Fondazione Piemonte Inst di Candiolo
RECRUITING

Candiolo, Italy
IRCCS - Istituto Nazionale dei Tumori
RECRUITING

Milan, 20133, Italy
IRCCS - Istituto Oncologico Veneto
RECRUITING

Padova, Italy
IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) "Dino Amadori"
RECRUITING

Meldola, Italy
Indiana Univ/Melvin and Bren Simon Cancer Center
WITHDRAWN

Indianapolis, Indiana, 46202, United States
Institut Catala d'Oncologia - ICO Badalona - Hospital Germans Trias i Pujol
RECRUITING

Barcelona, Spain
Institut Curie- Hopital de Paris
RECRUITING

Paris, 75248, France
Institut Gustave Roussy
RECRUITING

Villejuif, 94805, France
Institut du Cancer de Montpellier
WITHDRAWN

Montpellier, 34298, France
Istituto Clinico Humanitas
RECRUITING

Milan, Italy
Istituto Europeo di Oncologia
RECRUITING

Milan, Italy
James Graham Brown Ca Ctr at Univ of Louisville
RECRUITING

Louisville, Kentucky, 40202, United States
Jefferson Hospital
RECRUITING

Jefferson Hills, Pennsylvania, 15025, United States
Jersey Shore University Medical Center
RECRUITING

Neptune City, New Jersey, 07753, United States
John Theurer Cancer Center at From Road
RECRUITING

Paramus, New Jersey, 07652, United States
Johns Hopkins Univ/Sidney Kimmel Cancer Center
WITHDRAWN

Baltimore, Maryland, 21205, United States
Kanagawa Cancer Center
RECRUITING

Yokohama, Kanagawa, 241-8515, Japan
Kyushu University Hospital
RECRUITING

Higashiku, Fukuoka, 812-8582, Japan
LSU Health Baton Rouge-North Clinic
RECRUITING

Baton Rouge, Louisiana, 70805, United States
Laura and Issac Perlmutter Ca Ctr at NYU Langone
RECRUITING

New York, New York, 10016, United States
Leeds Teaching Hospitals NHS Trust - St. James's University Hospital
RECRUITING

Leeds, LS9 7TF, United Kingdom
Leiden University Medical Centre
RECRUITING

Leiden, 2300 RC, Netherlands
London Regional Cancer Center
RECRUITING

London, Ontario, N6A 4L6, Canada
Long Island Jewish Medical Center
RECRUITING

New Hyde Park, New York, 11040, United States
M D Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
Maria Sklodowska-Curie Memorial Cancer Centre - Maria Sklodowska-Curie National Research Institute of Oncology
RECRUITING

Warsaw, Poland
Marshfield Med Ctr-River Region at Stevens Point
RECRUITING

Stevens Point, Wisconsin, 54482, United States
Marshfield Medical Center
RECRUITING

Marshfield, Wisconsin, 54449, United States
Marshfield Medical Center
RECRUITING

Minocqua, Wisconsin, 54548, United States
Marshfield Medical Center
RECRUITING

Rice Lake, Wisconsin, 54868, United States
Marshfield Medical Center
RECRUITING

Weston, Wisconsin, 54476, United States
Marshfield Medical Center-EC Cancer Center
RECRUITING

Eau Claire, Wisconsin, 54701, United States
Masaryk Memorial Cancer Institute
RECRUITING

Brno, 656 53, Czechia
Mayo Clinic
RECRUITING

Rochester, Minnesota, 55905, United States
Mayo Clinic Hospital in Arizona
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic in Florida
RECRUITING

Jacksonville, Florida, 32224, United States
Medical College of Wisconsin
RECRUITING

Milwaukee, Wisconsin, 53226, United States
Moffitt Cancer Center
RECRUITING

Tampa, Florida, 33612, United States
Moffitt Cancer Center - McKinley Campus
RECRUITING

Tampa, Florida, 33612, United States
Moffitt Cancer Center-International Plaza
RECRUITING

Tampa, Florida, 33607, United States
Montefiore Medical Center - Moses Campus
RECRUITING

The Bronx, New York, 10467, United States
Montefiore Medical Center-Einstein Campus
RECRUITING

The Bronx, New York, 10461, United States
Mount Sinai Hospital
RECRUITING

Toronto, Canada
NHS Greater Glasgow and Clyde - Beatson West of Scotland Cancer Centre - Gartnavel General Hospital
WITHDRAWN

Glasgow, United Kingdom
NYU Langone Hospital - Long Island
RECRUITING

Mineola, New York, 11501, United States
Nagoya University Hospital
RECRUITING

Shōwaku, Nagoya, 466-8550, Japan
National Cancer Center Hospital
RECRUITING

Chuo-ku, Tokyo, 104-0045, Japan
National Cancer Institute
RECRUITING

Bratislava, SK 833 10, Slovakia
Nebraska Medicine-Bellevue
RECRUITING

Bellevue, Nebraska, 68123, United States
Nebraska Medicine-Bellevue
RECRUITING

Omaha, Nebraska, 68118, United States
Newcastle Hospitals - Freeman Hospital, Northern Centre For Cancer Care
NOT_YET_RECRUITING

Newcastle, NE7 7DN, United Kingdom
Niigata University Medical and Dental Hospital
RECRUITING

Niigata, Niigata, 951-8520, Japan
North Shore University Hospital
RECRUITING

Manhasset, New York, 11030, United States
Northwell Health/Center for Advanced Medicine
RECRUITING

Lake Success, New York, 11042, United States
Northwestern University
WITHDRAWN

Chicago, Illinois, 60611, United States
Nottingham University Hospitals NHS Trust - City Hospital
RECRUITING

Nottingham, NG5 1PB, United Kingdom
Ohio State University Comprehensive Cancer Center
RECRUITING

Columbus, Ohio, 43210, United States
Okayama University Hospital
RECRUITING

Kita-ku, Okayama-ken, 700-8558, Japan
Oregon Health and Science University
RECRUITING

Portland, Oregon, 97239, United States
Osaka International Cancer Institute
RECRUITING

Chuo-ku, Osaka, 541-8567, Japan
Our Lady of The Lake Hospital
RECRUITING

Baton Rouge, Louisiana, 70808, United States
Our Lady of the Lake Physician Group
RECRUITING

Baton Rouge, Louisiana, 70808, United States
Oxford University Hospitals NHS Trust - Churchill Hospital
WITHDRAWN

Oxford, OX3 7LE, United Kingdom
Pennsylvania Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
Peter Maccallum Cancer Institute
RECRUITING

Melbourne, Victoria, 3000, Australia
Policlinico Universitario Campus Bio-Medico- Oncology Center
RECRUITING

Roma, Italy
Princess Alexandra Hospital - University Of Queensland
RECRUITING

Woolloongabba, Queensland, QLD 4102, Australia
Radboudumc - Radboud University Medical Center Nijmegen
RECRUITING

Nijmegen, 6525, Netherlands
Renown Regional Medical Center
RECRUITING

Reno, Nevada, 89502, United States
Rhode Island Hospital
RECRUITING

Providence, Rhode Island, 02903, United States
Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States
Rush University Medical Center
RECRUITING

Chicago, Illinois, 60612, United States
Rutgers Cancer Institute of New Jersey
RECRUITING

New Brunswick, New Jersey, 08903, United States
Saint Vincent Hospital
RECRUITING

Erie, Pennsylvania, 16544, United States
Saitama Medical Center, Jichi Medical University
RECRUITING

Saitama, 330-8503, Japan
Sanford Bismarck Medical Center
WITHDRAWN

Bismarck, North Dakota, 58501, United States
Sanford Broadway Medical Center
WITHDRAWN

Fargo, North Dakota, 58122, United States
Sanford Cancer Center Oncology Clinic
WITHDRAWN

Sioux Falls, South Dakota, 57104, United States
Sanford Joe Lueken Cancer Center
RECRUITING

Bemidji, Minnesota, 56601, United States
Sanford Roger Maris Cancer Center
WITHDRAWN

Fargo, North Dakota, 58122, United States
Sanford USD Medical Center - Sioux Falls
WITHDRAWN

Sioux Falls, South Dakota, 57117, United States
Siteman Cancer Center-South Country
RECRUITING

St Louis, Missouri, 63129, United States
Siteman Cancer Center-West County
RECRUITING

Creve Coeur, Missouri, 63141, United States
Smilow Cancer Hospital Care Center - Guiford
RECRUITING

Guilford, Connecticut, 06437, United States
Smilow Cancer Hospital Care Center - Waterford
RECRUITING

Waterford, Connecticut, 06385, United States
Smilow Cancer Hospital Care Center - Westerly
RECRUITING

Westerly, Rhode Island, 02891, United States
Smilow Cancer Hospital Care Center at Glastonbury
RECRUITING

Glastonbury, Connecticut, 06033, United States
Smilow Cancer Hospital Care Center at Greenwich
RECRUITING

Greenwich, Connecticut, 06830, United States
Smilow Cancer Hospital Care Center at Long Ridge
RECRUITING

Stamford, Connecticut, 06902, United States
Smilow Cancer Hospital Care Center-Fairfield
RECRUITING

Fairfield, Connecticut, 06824, United States
Smilow Cancer Hospital Care Center-Trumbull
RECRUITING

Trumbull, Connecticut, 06611, United States
Smilow Cancer Hospital Care Ctr at Saint Francis
RECRUITING

Hartford, Connecticut, 06105, United States
Smilow Cancer Hospital-Derby Care Center
RECRUITING

Derby, Connecticut, 06418, United States
Smilow Cancer Hospital-Waterbury Care Center
RECRUITING

Waterbury, Connecticut, 06708, United States
Stony Brook University Medical Center
WITHDRAWN

Stony Brook, New York, 11794, United States
The Netherlands Cancer Institute-Antoni Van Leeuwenhoekziekenhuis
RECRUITING

Amsterdam, 1066, Netherlands
The Ottawa Hospital - General Campus
RECRUITING

Ottawa, Ontario, Canada
The Research Institute of the McGill University Health Centre
RECRUITING

Montreal, Quebec, H4A3J1, Canada
Thomas Jefferson University Hospital
RECRUITING

Philadelphia, Pennsylvania, 19107, United States
Tohoku University Hospital
RECRUITING

Sendai, Miyagi, 780-8574, Japan
UC Irvine Health/Chao Family Comprehensive Ca Ctr
RECRUITING

Orange, California, 92668, United States
UC San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States
UCHealth University of Colorado Hospital
RECRUITING

Aurora, Colorado, 80045, United States
UCI Health-Chao Family Comp CC and Ambulatory Care
RECRUITING

Irvine, California, 92612, United States
UPMC Hillman Cancer Center
RECRUITING

Pittsburgh, Pennsylvania, 15232, United States
UT Southwestern/Simmons Cancer Center-Dallas
RECRUITING

Dallas, Texas, 75390, United States
Univ of Florida Health Science Ctr - Gainesville
RECRUITING

Gainesville, Florida, 32610, United States
UniversitaetsMedizin Mannheim
RECRUITING

Mannheim, 68167, Germany
Universitaetsklinikum Carl Gustav Carus
WITHDRAWN

Dresden, 01307, Germany
Universitaetsmedizin Goettingen - Georg-August Universitaet
RECRUITING

Goettigen, Lower Saxony, 37075, Germany
University Hospital Motol
NOT_YET_RECRUITING

Prague, 150 06, Czechia
University Hospitals Birmingham - Queen Elisabeth Medical Centre
RECRUITING

Birmingham, B15 2TH, United Kingdom
University of Alabama at Birmingham Cancer Center
WITHDRAWN

Birmingham, Alabama, 35233, United States
University of Illinois at Chicago MBCCOP
RECRUITING

Chicago, Illinois, 60612, United States
University of Kansas Cancer Center
RECRUITING

Kansas City, Kansas, 66160, United States
University of Kansas Cancer Center-Overland Park
RECRUITING

Overland Park, Kansas, 66210, United States
University of Kansas Hospital-Westwood Cancer Ctr
RECRUITING

Westwood, Kansas, 66205, United States
University of Michigan Comprehensive Cancer Center
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
University of Oklahoma Health Sciences Center
RECRUITING

Oklahoma City, Oklahoma, 73104, United States
University of Pennsylvania/Abramson Cancer Center
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
University of Rochester
RECRUITING

Rochester, New York, 14642, United States
University of Tennessee - Knoxville
RECRUITING

Knoxville, Tennessee, 37920, United States
University of Vermont Medical Center
RECRUITING

Burlington, Vermont, 05401, United States
University of Washington Medical Center - Montlake
RECRUITING

Seattle, Washington, 98195, United States
UofL Health Medical Center Northeast
RECRUITING

Louisville, Kentucky, 40245, United States
VCU Community Memorial Health Center
WITHDRAWN

South Hill, Virginia, 23970, United States
VCU Massey Cancer Center at Hanover Medical Park
RECRUITING

Mechanicsville, Virginia, 23116, United States
VCU Massey Cancer Center at Stony Point
RECRUITING

Richmond, Virginia, 23235, United States
Vanderbilt University/Ingram Cancer Center
RECRUITING

Nashville, Tennessee, 37232, United States
Vermont Regional Cancer Center
RECRUITING

Burlington, Vermont, 05405, United States
Virginia Commonwealth Univ/Massey Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States
Washington University School of Medicine - Siteman Cancer Center
RECRUITING

St Louis, Missouri, 63110, United States
West Penn Hospital
RECRUITING

Pittsburgh, Pennsylvania, 15224, United States
Wexford Health and Wellness Pavilion
RECRUITING

Wexford, Pennsylvania, 15090, United States
Yale University
RECRUITING

New Haven, Connecticut, 06520, United States
Yale-New Haven Hospital North Haven Medical Center
RECRUITING

North Haven, Connecticut, 06385, United States
Yokohama City University Hospital
RECRUITING

Yokohama, Kanagawa, 236-0004, Japan
the Royal Marsden Hospital
RECRUITING

London, United Kingdom

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