Duke University

This study tests whether adding the drug selinexor to standard bispecific antibody therapy can help people with relapsed or refractory multiple myeloma achieve deeper remissions. About 27 adults who have already tried at least 4 prior treatments will take selinexor alongside thei…

This study tests whether a structured nutrition plan helps people recover physical function after abdominal trauma surgery. Participants are adults in the ICU who need nutrition through an IV. They are randomly assigned to either the structured plan (IV nutrition, then shakes for…

This study tests a program for older adults (65+) with cancer and mild memory issues, along with their spouse or caregiver. Over six video sessions, the pair learns strategies to manage challenges. The goal is to see if the program reduces distress and improves quality of life. A…

This study tests a program that teaches family caregivers how to help their loved ones with mild to moderate dementia manage chronic pain. Researchers will work with 60 people (30 patients and their caregivers) to see if the training improves pain coping and quality of life. The …

This study aims to find out how common acid reflux symptoms are in children with cystic fibrosis. Researchers will use a symptom questionnaire and, for some children, will stop their reflux medication to see if symptoms get worse. About 20 children aged 2 to 18 will take part.

This study tests a program to help doctors better screen for chronic kidney disease (CKD) in people with type 2 diabetes. Researchers will enroll 750 adults who are missing key lab tests for kidney health. The goal is to see if the program increases the number of patients who get…

This study looks at 200 high-risk pregnant women staying in the hospital. It compares two ways doctors do their daily rounds: the usual way with two visits (early morning and later) versus a single later-morning visit. The goal is to see if one approach makes patients feel better…

This study tests a new educational guide to help women with BRCA mutations decide whether to take hormone replacement therapy after having their ovaries and fallopian tubes removed to lower cancer risk. About 50 premenopausal women scheduled for this surgery will receive either t…