Case Western Reserve University
Clinical trials sponsored by Case Western Reserve University, explained in plain language.
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Zapping the brain to fight opioid addiction
Disease control Recruiting nowThis study is testing whether a combination of two non-invasive brain stimulation techniques can help people with opioid addiction and chronic pain. Participants will receive either real or fake stimulation while continuing their standard methadone treatment. The main goal is to …
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Apr 03, 2026 19:56 UTC
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Could a dental antibiotic help control diabetes?
Disease control Recruiting nowThis study is testing whether adding a slow-release antibiotic (Arestin) to a standard deep dental cleaning helps people with both type 2 diabetes and gum disease. Researchers want to see if this combined treatment improves gum health, lowers blood sugar levels, and reduces body-…
Phase: EARLY_PHASE1 • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Apr 02, 2026 15:01 UTC
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Silver vs. cement: the Long-Term fight against senior tooth decay
Disease control Recruiting nowThis study follows older adults for up to six years to see which of two cavity treatments works better long-term. One group gets a silver fluoride liquid painted on teeth, while the other gets a special filling cement plus fluoride varnish. The goal is to see which treatment is b…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Your phone could be your new blood pressure coach
Disease control Recruiting nowThis study is testing whether a smartphone app can help older African Americans better manage their high blood pressure. Researchers want to see if using the app for reminders and support helps people take their medications more consistently and improves their blood pressure read…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Could a Mother's womb sounds be medicine for preemies?
Disease control Recruiting nowThis study is testing whether playing specially designed womb-like sound recordings to premature babies in the NICU can help their brains develop better breathing control. Researchers want to see if these sounds reduce episodes where babies stop breathing (apnea), have low oxygen…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Doctors' offices test new system to fix America's dental care gap
Disease control Recruiting nowThis study tests a new system in primary care clinics to help older adults on Medicaid get to the dentist. Medical assistants will be trained to screen for oral health problems and make referrals during regular doctor visits. Researchers want to see if this approach leads to more…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Mar 19, 2026 14:55 UTC
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Brain and nerve zaps aim to bring back feeling to paralyzed hands
Disease control Recruiting nowThis study is testing whether small electrical pulses delivered to the brain or arm nerves can restore useful hand sensation in people with paralysis from spinal cord injury. Three participants who already have special electrodes implanted in their brain and arm will receive diff…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Can grocery delivery stop premature births?
Prevention Recruiting nowThis study is testing if delivering healthy groceries directly to the homes of pregnant women who struggle to afford food can improve their health and their babies' health. It will enroll 360 pregnant women in Ohio who are eligible for Medicaid. Researchers will compare different…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Prevention
Last updated Mar 19, 2026 14:56 UTC
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Can better fueling stop athlete burnout?
Prevention Recruiting nowThis study aims to prevent health and performance problems in college athletes caused by not eating enough. Researchers will provide 300 Division III athletes with nutrition screening and advice from sports dietitians throughout their season. The goal is to see if this support is…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Prevention
Last updated Mar 18, 2026 18:25 UTC
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Can a 6-Week class ease the burden on dementia caregivers?
Symptom relief Recruiting nowThis study is testing a 6-week online class called 'Learning Skills Together' designed to help family members caring for someone with Alzheimer's or another dementia. The program aims to teach practical caregiving skills to boost confidence and reduce feelings of depression and s…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Apr 03, 2026 19:55 UTC
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New hope for At-Risk LGBTQ+ youth: peers step in to prevent suicide
Symptom relief Recruiting nowThis study is testing whether peer support specialists—people with similar life experiences—can help LGBTQ+ youth who are at risk of suicide or self-harm. The program aims to connect 60 youth, aged 12-17, who are involved in systems like child welfare or juvenile justice, with ta…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Apr 02, 2026 14:56 UTC
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2-Hour therapy trial aims to ease trauma for assault survivors
Symptom relief Recruiting nowThis study is testing a new, single-session therapy designed to help college students who are struggling emotionally after experiencing a sexual assault. Researchers want to see if this 2-hour therapy session can reduce symptoms of PTSD and depression. The study will enroll 45 Oh…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Symptom relief
Last updated Mar 20, 2026 14:47 UTC
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Can learning to cook with what you have ease your mind and trash less food?
Knowledge-focused Recruiting nowThis study is testing a new type of cooking class that teaches people how to cook with ingredients they already have, store food properly, and waste less. Researchers want to see if these skills can help adults feel less stressed and improve their diet. The study will involve abo…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC