Case Western Reserve University

This study looks at whether adding Arestin (tiny antibiotic beads) to standard deep cleaning can improve gum healing and blood sugar levels in adults with type 2 diabetes and gum disease. About 42 participants will receive either deep cleaning alone or deep cleaning plus Arestin.…

This study follows 480 older adults in low-income housing to see which treatment works better long-term for stopping tooth decay: a silver diamine fluoride liquid painted on teeth, or a standard filling plus fluoride varnish. Participants are aged 62 and older and will be checked…

This study compares two surgical techniques to treat receding gums on the lower front teeth. About 36 adults with gum recession will receive either a standard method (coronally advanced flap with connective tissue graft) or a newer method (gingival pedicle split thickness flap wi…

This study tests whether smartphone apps and text messages can help African American adults aged 50 and older better manage their blood pressure and stick to their medications. High blood pressure is a major health issue for this group, and the goal is to see if technology can ma…

This study looks at whether delivering medically tailored groceries to pregnant women on Medicaid can reduce food insecurity and improve pregnancy outcomes, like preventing preterm birth and low birthweight. About 360 pregnant women in Cuyahoga County, Ohio, will receive free gro…

This study compares two ways of placing dental implants for upper dentures: loading them right away versus waiting 3 months. Researchers will track bone loss, implant success, and patient satisfaction over 3 years. The study involves 18 adults with no upper teeth who already wear…

This study tests a new, single-session therapy called PATH-SS for people who have experienced sexual assault. It aims to reduce symptoms of PTSD and depression. About 45 adults in Ohio will receive the therapy and be followed for one month to see if symptoms improve.

This study is testing whether a non-invasive brain stimulation technique (tDCS combined with ultrasound) can reduce drug use and improve well-being in people with opioid use disorder and chronic pain. About 126 adults on methadone treatment will receive either real or sham stimul…

This pilot study tests a sleep improvement program designed specifically for family caregivers. Researchers want to see if combining cognitive behavioral therapy, mindfulness, and caregiving guidance can help 30 caregivers sleep more regularly, feel more rested during the day, an…

This study looks at whether playing womb-like sounds to preterm infants can help their brains mature and improve breathing control. Researchers will monitor 34 babies born at 29-33 weeks for breathing pauses, low oxygen, and slow heart rate. The goal is to understand how sound af…

This study looks at whether trained peer support specialists can help LGBTQ+ youth (ages 12-17) who are involved with juvenile justice, child welfare, or mental health services and have thoughts of suicide or self-harm. The goal is to see if this approach is practical and helps w…

This study looks at how tiny electrical pulses to the brain or arm nerves can help people with spinal cord injury feel touch and pressure in their hands again. Only 3 people who already have electrodes implanted from a larger study will take part. Researchers will test different …

This study aims to improve how we screen and support nutrition in college athletes. Researchers will measure things like height, weight, and grip strength, and ask athletes to fill out questionnaires. A sports dietitian will then give personalized nutrition advice. The goal is to…

This study looks at whether training medical staff and updating electronic health records can encourage older adults (55+) on Medicaid to visit the dentist more often. About 929 participants from 12 clinics will be split into two groups: one gets enhanced support and education, t…