Could gentle brain zaps curb opioid cravings and ease pain?
NCT ID NCT04379115
First seen Jan 16, 2026 · Last updated May 23, 2026 · Updated 17 times
Summary
This study is testing whether a non-invasive brain stimulation technique (tDCS combined with ultrasound) can reduce drug use and improve well-being in people with opioid use disorder and chronic pain. About 126 adults on methadone treatment will receive either real or sham stimulation over several weeks. The goal is to see if this approach helps lower cravings and pain without surgery or medication.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Spaulding Rehabilitation Hospital - 5th Floor - Neuromodulation Center
RECRUITINGCambridge, Massachusetts, 02138, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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University Hospitals Cleveland Medical Center/ Dahms Clinical Research Unit
RECRUITINGCleveland, Ohio, 44106-1716, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Illinois Health/ University of Illinois at Chicago
RECRUITINGHinsdale, Illinois, 60612, United States
Contact Email: •••••@•••••
Contact
Contact Email: •••••@•••••
Conditions
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