Baptist Health South Florida

This study tests a combination of two drugs (zanubrutinib and pemetrexed) followed by zanubrutinib alone for people with a type of brain lymphoma that has returned or not responded to prior treatment. The goal is to see how well the treatment shrinks tumors and controls the disea…

This study tests whether giving radiation therapy early to people with spine tumors that are not yet causing serious pain can prevent future problems like fractures, spinal cord compression, or the need for emergency surgery. About 74 adults with advanced solid tumors and at leas…

This study tests whether adding the drug azeliragon to targeted radiation therapy can safely shrink brain tumors and keep them from growing back. About 46 adults with cancer that has spread to the brain will take part. The goal is to improve tumor control, not to cure the disease…

This study tests whether adding the drug ruxolitinib to standard treatment (radiation and temozolomide) helps people with newly diagnosed glioblastoma live longer. About 190 adults will be randomly assigned to receive either the standard treatment alone or standard treatment plus…

This study tests how well a short course of hormone therapy (ADT) shrinks high-risk prostate cancer before surgery. About 50 men will get ADT, then have PSMA PET scans to see if the cancer shrinks. The goal is to see if this approach can improve outcomes after prostate removal.

This study tests the drug cabozantinib in people whose meningioma (a type of brain tumor) has come back or is growing despite standard treatments. About 24 adults with any grade of meningioma will receive the drug to see if it can stop or slow tumor growth. The main goal is to me…

This study tests whether adding Tumor Treating Fields (TTF) to targeted radiation therapy can slow tumor growth in people with locally advanced pancreas cancer. Participants receive radiation for five days and use a wearable TTF device for at least 18 hours daily. The goal is to …

This study is for people with cancer that has spread to the spine. Instead of the usual 1 or 2 high-dose radiation sessions, researchers are testing a 5-session approach that gives smaller doses each time. The goal is to see if this method is easier to tolerate and still provides…

This study tests if a mouth rinse called MucoLock can safely reduce mouth pain or burning in adults with stomatitis. About 25 people will use it like a mouthwash three times a day for 28 days. The main goal is to see if pain scores improve.

This study looks at whether a special PET scan using an investigational agent called 18F-Fluciclovine can find leftover tumor in people who had brain metastasis surgery and are scheduled for radiation. About 20 adults will get an optional PET scan before radiation. The goal is to…

This study is testing whether a special PET scan using 18F-Fluciclovine can help doctors see how brain tumors respond to a precise type of radiation called stereotactic radiosurgery (SRS). About 46 adults with brain metastases (tumors that spread from other cancers) will get the …

This study collects samples of glioblastoma (a type of brain tumor) and blood from 120 adults during standard surgery. Researchers will examine tissue from different parts of the same tumor to see how they differ. The goal is to learn more about the tumor's structure and behavior…

This study is testing whether a smartphone app can reliably measure thinking and memory changes in 200 adults with brain tumors. Participants will use the app to complete memory, attention, and problem-solving tests, and report their quality of life. The goal is to see if these d…

This study looks at whether a special imaging agent called 18F-fluciclovine can help doctors see if radiation therapy is working on large brain tumors that have spread from other cancers. About 20 adults with at least one untreated brain tumor larger than 2 cm will get PET/CT sca…