Adventhealth

This study tests two techniques to reduce the chance that large colon polyps will grow back after being removed during a colonoscopy. About 342 adults with polyps at least 20 mm wide will take part. The goal is to see which method works better at preventing recurrence.

This early-phase trial tests whether giving two drugs (darolutamide and relugolix) before prostate cancer surgery is safe and practical for men with high-risk prostate cancer. About 30 adult men will receive the drug combination for a short time before their prostate is removed. …

This study follows 600 adults who are already scheduled to have a standard procedure called POEM to treat swallowing or stomach muscle problems. Researchers will track how well the procedure works over time and how often side effects like acid reflux occur. No new treatments are …

This study tests whether a 4-week digital brain-training program can reduce apathy (loss of interest or motivation) in adults aged 60 and older with major depression. Participants will use a customized computer program designed to improve brain connections linked to motivation an…

This study tests whether a whole-food, plant-based diet (no added oils) can reduce painful diabetic neuropathy. About 40 adults with type 2 diabetes or prediabetes and nerve pain will be randomly assigned to either the diet or standard pain medication. The goal is to see if impro…

This study tests a retreat program called RISE for nurse managers who feel burned out or stressed. Researchers want to see if the retreat is practical and helpful for improving well-being. The study will include 16 nurse managers from AdventHealth who have moderate to high burnou…

This study compares two procedures to relieve a stomach blockage caused by cancer: a newer method using an endoscope (EUS-GJ) and traditional surgery (S-GJ). About 70 adults with advanced cancer who cannot eat normally will be randomly assigned to one of the two procedures. The g…

This study tests an 8-week program called HEAL-GYN for people who have finished chemotherapy for gynecologic cancer. The program focuses on healthy eating and physical activity to improve confidence, mental health, and overall well-being. Researchers will measure changes in eatin…

This study is tracking how well a procedure called endoscopic submucosal dissection (ESD) works for removing abnormal growths in the esophagus and other parts of the digestive tract. Researchers will follow 1,000 adults who are already scheduled for this procedure as part of thei…

This study watches how well a medical clip works to close bleeding, holes, or fistulas in the digestive tract during standard endoscopy. About 250 adults will take part, and no experimental treatments are given. The goal is to see how often the clip fully closes the problem area.

This study tests a community-based program to help underserved adults get screened for lung, breast, and prostate cancers. About 200 people who meet screening guidelines will be offered navigation support at community resource spots. The goal is to see if this approach increases …