Abbott Medical Devices

This study tested whether a special pacing feature called SyncAV helps people with congestive heart failure more than standard pacing. About 1,686 adults who needed a new heart device took part. The goal was to see if SyncAV improves heart function and reduces symptoms over 12 mo…

This study follows over 3,400 people who already have an Aveir VR leadless pacemaker to see how safe it is over the long term (up to 10 years). The pacemaker helps control slow or irregular heartbeats. Researchers track complications shortly after implant and for years afterward …

This study looks at a device called the AMPLATZER PFO Occluder, which is used to close a small hole in the heart (PFO) that may have caused a stroke. Researchers want to confirm it is safe and effective at preventing another stroke over five years. About 1,200 people who had a st…

This study tests a new device called the Navitor TAVI system, which replaces a narrowed heart valve without open-heart surgery. It includes up to 1,500 people with severe aortic stenosis who are at low or intermediate risk for surgery. The goal is to see if the device is safe and…

This study tests a special plug device to close leaks that can form around surgically placed heart valves. These leaks can cause serious problems like heart failure or anemia. The goal is to see if the device can safely reduce the leak and improve symptoms without needing another…

This study tests a new device called the Amulet 2, which is placed in the heart to seal off a small pouch where blood clots often form in people with atrial fibrillation (AF). The goal is to lower the risk of stroke without needing lifelong blood-thinning medication. About 458 ad…

This study looks at how safe and effective a special catheter (FlexAbility SE) is for treating ventricular tachycardia, a fast, dangerous heart rhythm. About 62 people with heart disease who have not gotten better with medication will take part. Researchers will track serious sid…

This study tests a new device called the Esprit BTK System, which is a small mesh tube that releases medicine to keep leg arteries open. It is for people with critical limb ischemia, a severe condition where blocked arteries cause pain and risk of amputation. About 261 participan…

This early study tested a new balloon-expandable heart valve system (TAVI) in 8 people with severe aortic stenosis who were at increased risk for surgery. The goal was to see if doctors could successfully deliver and use the device. The study is active but no longer recruiting, a…

This study is testing a new type of pacemaker that doesn't use wires (leads) to help people with a slow heartbeat. About 20 adults who need a pacemaker will get this device and be checked for safety and performance at 1 and 3 months. The goal is to see if the leadless pacemaker w…

This study tests a new device system (TactiFlex SE catheter and Volt generator) that uses pulsed field ablation to treat paroxysmal atrial fibrillation, a type of irregular heartbeat. The goal is to see if the procedure is safe and effective for people whose symptoms haven't impr…

This study follows 200 people with persistent atrial fibrillation (a type of irregular heartbeat) to see how well a catheter-based treatment works over time. The treatment uses radiofrequency energy to fix the heart's electrical signals. Researchers will check if the heart stays …

This study tested a new device called the Tendyne mitral valve, which is implanted without open-heart surgery to treat a leaky mitral valve (mitral regurgitation). About 103 people with moderate-to-severe symptoms took part, and some were compared to those receiving an existing d…

This study looks at how well a device called TriClip works and how safe it is for people with a leaky heart valve (tricuspid regurgitation). About 1000 adults who are already eligible for the device will be followed to track complications and heart function improvements. The goal…

This study tests if a device called the Amulet, which closes a small pouch in the heart, is as safe and effective as daily blood thinner pills for preventing strokes in people with atrial fibrillation. About 2,650 participants will be randomly assigned to get the device or take s…

This study tests a new type of lead for implantable heart devices (ICD or CRT-D) that helps pace the heart's natural conduction system. It includes up to 414 adults with heart failure or dangerous heart rhythms who need a new device. The goal is to see if the lead is safe and wor…

This study looks at how well the Abbott TriClip device works in real-world patients with severe tricuspid regurgitation, a condition where a heart valve leaks. Researchers followed 511 adults who received the device to see if it successfully reduced the leak and improved outcomes…

This study is testing a small mechanical heart valve (15mm) designed for children who need their aortic valve replaced. Researchers are following 20 kids for up to 5 years to see how safe and effective the valve is. The goal is to track serious side effects and how well the valve…

This study tests a new heart valve (NAVITOR) placed using a tube through a blood vessel (TAVR) in 434 people with severe aortic stenosis. The main goals are to check for valve leakage after 30 days and to see how many people have serious problems like death or disabling stroke wi…

This study tests a new balloon-expandable heart valve (TAVI) for people with severe aortic stenosis, a condition where the heart's aortic valve is narrowed. The goal is to see if the device is safe and works as intended. Only 11 adults with severe symptoms are taking part.

This study looks at a device called Esprit BTK, a scaffold that slowly dissolves, used to open blocked leg arteries in people with chronic limb-threatening ischemia (CLTI), a serious condition that can lead to amputation. About 200 participants will be followed to see if the devi…

This study looks at how well the Amulet device works in everyday medical practice to prevent stroke in people with atrial fibrillation (an irregular heartbeat). Over 600 participants at 16 U.S. sites were followed for 2 years. Researchers tracked complications, device closure suc…

This study looks at a larger version of a heart stent (a tiny mesh tube) used to open blocked arteries in people with coronary artery disease. Researchers want to see if it stays safe and works well when used in everyday medical practice. About 100 people took part, and the main …

This study looks at how safe and effective a device called the Amplatzer Piccolo Occluder is for closing a common heart hole (PDA) in small babies. About 70 babies weighing at least 700 grams will be followed for 6 months after the procedure. The goal is to track any complication…

This study tests a new system that uses pulsed field ablation to treat atrial fibrillation, a common heart rhythm problem. About 300 people with symptoms that haven't improved with medication will receive the procedure. The goal is to see if it safely and effectively restores a n…

This study tests whether a less invasive device called MitraClip works as well as open-heart surgery to fix a severe leaky heart valve (mitral regurgitation) in people who are at moderate risk from surgery. About 500 participants will be randomly assigned to get either the clip o…

This study gathers extra health information from wearable devices and a smartphone app in 80 people with heart disease who already have a special implanted heart device. The goal is to see if this additional data can help doctors better understand and track heart health over time…

This study looks at how a drug called everolimus moves through the blood after a device (Esprit BTK) is placed in leg arteries below the knee. It involves about 7 people with severe leg pain or wounds due to blocked arteries. Researchers take blood samples at many time points ove…