WOUNDS AND INJURIES

This study is testing a new device called WounDx™ that gives surgeons information about a wound to help them decide the best time to close it. The device is experimental and not yet approved by the FDA. About 40 people with large wounds on their arms or legs will take part. The f…

This study compares a new powder dressing (Altrazeal) to standard dressings for treating partial-thickness burns in adults. The goal is to see if it reduces pain during dressing changes and helps wounds heal faster. Participants are adults aged 18-65 with burns covering less than…

This study tests whether a drug called 4-aminopyridine (4-AP) can help skin wounds heal faster. Researchers will give the drug to 150 healthy adults and measure how quickly small biopsy wounds close. The goal is to find a safe, new way to treat both chronic and acute wounds.

This study looks at whether providing medically tailored meals and shakes for 12 days after orthopedic trauma surgery can improve healing and nutrition. About 75 adults who live in certain Los Angeles zip codes will receive the meals at home through Meals on Wheels. Researchers w…

This study tests whether acupuncture can help relieve symptoms of Gulf War Illness, a condition affecting many veterans. Two hundred veterans will receive either biweekly acupuncture for six months or a shorter waitlist followed by weekly treatments. The goal is to see if acupunc…

This study tests whether a cream made from 4-aminopyridine (4-AP) can help second-degree burns heal faster and with less scarring. About 200 adults with fresh burns will receive the cream or a placebo. The goal is to see if the treatment reduces the need for skin grafts and impro…

This study explores whether skin can be changed from one type to another, specifically making normal skin more like the thick skin on palms and soles. Researchers will inject participants' own skin cells (fibroblasts) into small areas and later remove the skin for lab analysis. T…

This study looks at whether a bedside ultrasound called FAST can safely lower the number of CT scans needed for children with blunt belly injuries. About 4,346 kids under 18 will be randomly assigned to get either standard care or standard care plus a FAST exam. The goal is to se…

This study aims to create a smart computer program that helps doctors better understand the sounds from a handheld device used to check blood flow in arteries. Many doctors have little training in using this device, which can lead to mistakes or delays in diagnosing problems like…

This study aims to find out if doctors who complete Advanced Trauma Life Support (ATLS) training can save more lives of adult trauma patients compared to standard care. Over 4,000 patients in Indian hospitals will be included. Researchers will track deaths within 30 days of arriv…