URINARY TRACT INFECTIONS

This study tests a new vaccine designed to prevent urinary tract infections (UTIs) caused by E. coli bacteria. Researchers will first check safety and immune response in 448 adults aged 18-64, then measure how well it works in women of the same age. Participants receive either th…

This study tests a new treatment called LBP-EC01, made from viruses that attack bacteria, for urinary tract infections (UTIs) caused by drug-resistant E. coli. About 318 adults with a history of UTIs will receive either the virus treatment plus an antibiotic, or a placebo plus th…

This study tests whether a single injection of the antibiotic amikacin can effectively treat uncomplicated bladder infections in women visiting the emergency department. Instead of taking pills for 3-7 days, participants receive one shot into a muscle or vein. The goal is to see …

This study tests two approaches to prevent repeat bladder infections in 100 women over 40 who have gone through menopause. One group takes a nightly antibiotic for 6 months, while the other uses a vaginal tablet containing good bacteria and a low-dose hormone. The goal is to see …

This study looks at whether giving antibiotics by mouth (orally) works as well as giving them through a vein (IV) for people who come to the emergency room with common infections like pneumonia, urinary tract infections, or skin infections. About 4,000 adults will take part, and …

This study compares a new DNA test (PCR) to the standard urine culture for diagnosing urinary tract infections (UTIs) in adults. About 136 participants with UTI symptoms will be randomly assigned to one of the two testing methods. The goal is to see if the DNA test leads to faste…

This study tests a new DNA-based method (Next Generation Sequencing) to detect bacteria in urine from women with UTI symptoms whose standard urine culture shows very few bacteria. The goal is to see if this advanced technique can find hidden infections and guide better treatment.…

This study looks at whether a 21-day spa program, including mineral water baths and exercise, can help people with chronic kidney and urinary tract problems. Researchers will check 150 adults (ages 40-70) before and after treatment using blood tests, urine tests, and quality-of-l…

This early-stage study is testing a new drug called JKN2501 in 66 healthy adults in China to see if it is safe and how the body processes it. The drug is being developed to fight bacterial infections like urinary tract, lung, and abdominal infections. Participants will receive ei…

This study tests a prediction model to help doctors decide when antibiotics are truly needed for urinary tract infections (UTIs) in the emergency room. About 47 women discharged from the ER with a UTI diagnosis will be enrolled. The goal is to reduce unnecessary antibiotic use an…

This study looks at whether scheduling automatic follow-up appointments after a child leaves the hospital is better than letting parents decide if one is needed. About 2,674 children hospitalized for infections like pneumonia or urinary tract infections will take part. The goal i…