ULCERATIVE COLITIS (UC)

This study tested a new drug called IBI112 in 150 people with moderate to severe ulcerative colitis, a chronic bowel disease. The goal was to see if IBI112 could help patients achieve remission (symptom-free period) after 12 weeks of treatment. Participants were randomly assigned…

This study tested the effectiveness and safety of VedAryo® (vedolizumab) in 150 people with inflammatory bowel disease (ulcerative colitis or Crohn's disease). Participants received the drug and were followed for 52 weeks. The goal was to see if symptoms improved and to track any…

This study looked at 81 people with severe ulcerative colitis to see if starting upadacitinib early works better than using it after other treatments fail. Researchers compared how many patients avoided surgery and achieved remission. The goal is to find the best timing for this …

This study tested a 15-day diet rich in high-fiber foods, fermented foods, and berries in 36 healthy adults and adults with inactive (quiescent) ulcerative colitis. Participants provided blood, stool, and urine samples, and filled out questionnaires about their symptoms and quali…

This study looked at whether differences in the IL-7R gene are linked to developing ulcerative colitis (UC) and how well patients respond to the drug vedolizumab. Researchers compared 898 people with UC and healthy controls. The goal is to better understand who might benefit most…

This study looked at 100 people with ulcerative colitis to see if two blood-based scores, called CALLY and HAALP, can help doctors tell when the disease is active. The goal was to find a simple way to measure inflammation without invasive tests. The study is complete, but it only…

This completed study examined whether differences in the BAFF gene are linked to the risk of developing ulcerative colitis and how well the drug vedolizumab works. Researchers analyzed DNA from 841 people with ulcerative colitis to identify gene patterns. The goal was to better u…

This study looked back at 159 people with ulcerative colitis who started a new advanced treatment. Researchers wanted to see if checking tissue samples under a microscope (histology) could predict who would later need stronger treatment, a hospital stay, or surgery. They compared…

This study looked at 366 adults referred to the hospital with suspected inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis. The goal was to find simple, non-invasive markers that can help doctors diagnose IBD more accurately and predict how the dis…

This completed study looked at whether four free self-help resources—a book, a smartphone app, a help center, and a peer mentor—can help adults with Crohn's disease or ulcerative colitis feel more in control and reduce disability. Over 800 people with moderate-to-severe IBD-relat…