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Can a High-Fiber diet soothe ulcerative colitis? new study tests UC-TREAT

NCT ID NCT06998277

Disease control Sponsor: University of Glasgow Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a 15-day diet called UC-TREAT, rich in high-fiber foods, fermented foods, and berries, in 36 adults—some healthy and some with quiescent (inactive) ulcerative colitis. Researchers measured changes in gut bacteria, digestive symptoms, and diet acceptability. The goal was to see if this diet could improve gut health without causing discomfort.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
UC-TREAT diet (high-fiber foods, fermented foods, berries, and a multivitamin-multimineral tablet)
What this could lead to
If the diet is well-tolerated and improves gut health, it could point toward a dietary approach to help manage ulcerative colitis during remission.
What could go wrong
This is a small, early-stage study with only 36 participants and no control group, so results may not apply broadly. The diet may be hard to follow or cause digestive discomfort.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

36 people

The number who actually took part.

Started

May 2024

Finished

Jul 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Individuals with Ulcerative Colitis: * Confirmed diagnosis of Ulcerative Colitis * ≥16 years of age * Motivated to follow the prescribed diet for the study period Healthy controls: * ≥16 years of age * Motivated to follow the prescribed diet for the study period Exclusion Criteria: Individuals with Ulcerative Colitis: * Self-reported active disease (SCCAI≥5) and/or a score ≥2 on any variable within SCCAI * Previous surgery related to their UC (e.g. colectomy) * Adjustment of medication dose in the previous month * Initiation of a new medication in the prior 3 months * BMI≥35kg/m2 * Pregnancy or lactation * Regular use of pre/probiotic supplements * Antibiotics or steroid use in the past 2 months * Weight fluctuations ≥ 2kg in the past month * Dietary restrictions (vegetarian, vegan, gluten-free etc) * Participation in other interventional research. Healthy controls: * Regular use of medication or regular visits to a physician * History of gut surgery * BMI≥35kg/m2 * Pregnancy or lactation * Regular use of pre/probiotic supplements * Antibiotics or steroid use in the past 2 months * Weight fluctuations ≥ 2kg in the past month * Dietary restrictions (vegetarian, vegan, gluten-free etc) * Participation in other interventional research.

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Conditions

The condition(s) this trial relates to.

ulcerative colitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Ulcerative colitis (UC)

Contacts and locations

Locations

  • University of Glasgow

    Glasgow, G31 2ER, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.